Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.ezh2emHorb | X. tropicalis | ezh2 | CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans... | |
| Xtr.eya1emNXR | X. tropicalis | eya1 | CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... | |
| Xtr.eya1em1NXR | X. tropicalis | eya1 | CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... | |
| Xtr.erfemHorb | X. tropicalis | erf | CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission. Custom mutant gene... | |
| Xtr.eomesemHorb | X. tropicalis | eomes | CRISPR knockout of eomes (eomesodermin). Germ line transmission confirmed. gRNA targets exon 1 and 2... | |
| Xtr.eomesem2Horb | X. tropicalis | eomes | 2nd CRISPR knockout of eomes (eomesodermin), carrying a 4bp deletion. Custom mutant generated by Ho... | |
| Xtr.dtlemHorb | X. tropicalis | dtl | CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... | |
| Xtr.dstmZimml | X. tropicalis | unknown | Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... | |
| Xtr.dmrt1emNXR | X. tropicalis | dmrt1 | Xtropicalis CRISPR knockout of dmrt1 (doublesex and mab-3 related transcription factor 1). Germ line... | NXR |
| Xtr.cybbemHorb | X. tropicalis | cybb | CRISPR knockout of cybb (cytochrome b-245, beta polypeptide). Germ line transmission not confirmed. ... | NXR |
| Xtr.csnk1g2emNXR | X. tropicalis | csnk1g2 | CRISPR knockout of csnk1g2 (casein kinase 1 gamma 2). Germ line transmission confirmed. Mutation is ... | NXR |
| Xtr.celf3emNXR | X. tropicalis | celf3 | CRISPR knock out of celf3 (CUGBP, Elav-like family member 3). Germ line transmission not yet confirm... | NXR |
| Xtr.cby1emNXR | X. tropicalis | cby1 | TALEN knockout of cby1 (chibby homolog 1). Germ line transmission not confirmed. Mutation not charac... | NXR |
| Xtr.cbsemNXR | X. tropicalis | cbs | Custom CRISPR generated by NXR, targeting the cbs (cystathionine-beta-synthase) gene, | NXR |
| Xtr.cacna1hem2NXR | X. tropicalis | cacna1h | CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... | NXR |
| Xtr.cacna1hem1NXR | X. tropicalis | cacna1h | CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... | NXR |
| Xtr.bxemZimml | X. tropicalis | unknown | Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations. | |
| Xtr.bunmZimml | X. tropicalis | unknown | Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations. | |
| Xtr.bicc1em2NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | |
| Xtr.bicc1em1NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | NXR |
| Xtr.bhlhe22emHorb | X. tropicalis | bhlhe22 | CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... | |
| Xtr.bcorem4Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 11bp dele... | |
| Xtr.bcorem3Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 5bp delet... | |
| Xtr.bcorem2Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 1bp delet... | NXR |
| Xtr.bcorem1Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 4bp delet... | |
| Xtr.bace1emHorb | X. tropicalis | bace1 | CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for ... | |
| Xtr.atp7amZimml | X. tropicalis | atp7a | A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... | |
| Xtr.askmZimml | X. tropicalis | unknown | Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... | |
| Xtr.ascl1emHorb | X. tropicalis | ascl1 | CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... | |
| Xtr.arnt,arnt2emHorb | X. tropicalis | arnt | CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... | |
| Xtr.apcMRCΔ1/+Vlemx | X. tropicalis | apc | F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri... | |
| Xtr.ap3d1mZimml | X. tropicalis | ap3d1 | Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... | |
| Xtr.amhem3NXR | X. tropicalis | amh | 3rd of 3 different X. tropicalis CRISPR knockout lines targeting amh (anti-Mullerian hormone ) dev... | NXR |
| Xtr.amhem2NXR | X. tropicalis | amh | 2nd of 3 different X. tropicalis CRISPR knockout lines targeting amh (anti-Mullerian hormone ) deve... | NXR |
| Xtr.amhem1NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. Animals carry a +8... | NXR |
| Xtr.amhr2emNXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... | |
| Xtr.aif1lem2Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | NXR |
| Xtr.aif1lem1Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.ahrem2NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti... | NXR |
| Xtr.ahrem1NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... | |
| Xtr.acsl1emNXR | X. tropicalis | acsl1 | CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co... | |
| Xtr. lrrk2emNXR | X. tropicalis | lrrk2 | CRISPR knockout fo CRISPR knockout fo (leucine-rich repeat kinase 2 ). Germ line transmission confir... | |
| Xla.xdm-wemNXR | X. laevis | dm-w.L | CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi... | |
| Xla.wnt3em2NXR | X. laevis | wnt3.L | X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... | |
| Xla.wnt3em1NXR | X. laevis | wnt3.S | X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... | NXR |
| Xla.wnt11emHorb | X. laevis | wnt11.L wnt11.S | Double CRISPR knockout of wnt11 (Wnt family member 11) in X. laevis, Confirmed germline transmission... | NXR |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp de... | NXR |
| Xla.wdpcpemHorb | X. laevis | wdpcp.L | CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio... | NXR |
| Xla.velo1emNXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized . Germ lin... | NXR |
| Xla.tyremNXR | X. laevis | tyr.L | TALEN induced tyrosinase mutant. Custom line made by the NXR. Contact NXR for details. |
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