Gene Symbol: hsp70 Gene Name: heat shock 70kDa protein Synonyms: xhsp70 Add Xenopus synonyms Gene Function: molecular chaperone Interactants: hspa8(15) , hsp90aa1.1(12) , hsf1(10) , myh4(9) , hsp90b1(6) , hspa5(5) , bmp4(4) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001112899|Xenopus (Silurana) tropicalis heat shock 70kDa protein (hsp70), mRNA CAGCTGCACATATACAAGCGGAAAGTGTGAAGAAACTCTAAGGAGCAGAAACATGGCATCCAAAGGAGTCGCAGTTGGCATTGATCTCGGCACTACCTACTCCTGCGTTGGTGTTTTCCAGCATGGTAAAGTAGAGATCATCGCTAATGACCAAGGGAATCGCACCACTCCTAGCTATGTGGCTTTCACAGATACAGAAAGGTTGATTGGTGATGCAGCCAAGAATCAAGTGGCAATGAATCCCCAGAATACAGTCTTTGATGCTAAGAGACTTATAGGAAGAAAGTTTAATGATCCCGTCGTTCAGTCAGACCTGAAGCACTGGCCGTTCCAAGTGGTAAGCGATCATGGGAAGCCAAAGGTTAAAGTGGAGTTTAAAGGAGAGGAGAAAACCTTCTTTCCCGAGGAGATCTCATCTATGGTGCTTATAAAGATGAAAGAGACAGCAGAAGCTTACCTGGGCCACGCTGTTACCAATGCTGTTATTACTGTGCCAGCCTACTTTAATGATTCTCAGAGACAGGCCACAAAGGATGCTGGTGTCATTGCAGGACTAAATGTTTTGAGAATCATCAATGAGCCTACAGCAGCTGCTATTGCTTATGGCCTAGATAAAGGAACCAGAGGAGAGCGCAATGTTCTTATCTTTGATTTGGGAGGTGGAACATTCGATGTCTCCATCCTTACTATAGATGATGGCATCTTTGAAGTTAAGGCAACAGCAGGTGACACACATCTAGGTGGAGAAGACTTTGACAATCGTATGGTCAATCATTTTATGGAGGAATTCAAGCGAAAACACAAGAAGGATATCAGCCAGAACAAAAGAGCTCTAAGGAGGCTGAGGACAGCCTGTGAGCGAGCCAAGCGCACCCTGTCATCCAGTAGCCAGGCAAGCATTGAAATTGACTCCCTGTTTGAAGGTATTGACTTCTACACATCCATCACCAGGGCCCGCTTTGAAGAACTGTGCTCTGACCTCTTCAGGGGTACATTGGAACCTGTGGAAAAGGCTCTGAGAGACGCCAAGTTGGACAAATCACAGATAGATGAGATTGTCCTTGTGGGAGGTTCCACACGCATTCCTAAAGTGCAAAAATTGCTTCAAGACTTCTTTAATGGCAGAGAGCTAAACAAGAGCATAAATCCTGATGAAGCTGTGGCATATGGAGCTGCTGTACAGGCTGCCATCCTAATGGGTGACAAATCAGAGAATGTGCAAGACTTACTTCTGCTGGATGTTGCACCTTTATCACTGGGCTTGGAGACAGCAGGAGGAGTAATGACTGTGCTTATCAAACGAAACACAACTATCCCAACCAAGCAGACACAGACCTTTACAACATACTCTGACAATCAGCCTGGTGTACTTATCCAGGTGTTTGAGGGAGAGAGGGCTATGACCAAAGACAATAATCTTTTGGGGAAGTTTGAGTTAAGTGGAATTCCCCCTGCTCCTAGAGGAGTTCCTCAGATTGAAGTCACCTTTGACATTGATGCTAATGGCATACTAAATGTTTCTGCTGTGGAAAAGAGCTCTGGCAAACAGAATAAGATTACAATTACAAATGACAAAGGGCGGCTGAGTAAAGAGGACATTGAAAAGATGGTACAGGAGGCAGAAAGGTACAAGGCTGATGATGATGCTCAAAGAGAAAAGATTGATGCCAAAAACTCACTAGAATCTTATGCCTTTAACTTAAAAAGCATGGTAGAAGATGAAAATATGAAGGGCAAAATCAGTGAAGGAGACAAAAGAATTATTTCAGAGAAATGCACACAGATAATTTCCTGGCTTGAAAACAACCAGCTGGCAGAGAAAGACGAGTATGCCTTCCAGCAAAAAGAACTAGAGAGGGTATGCCAACCTATTATTACAAAACTGTATCAAGGCAGTATGCCAGGAAGCATGCCAGGTTCTAGCTGTGGTGCTCAGGCCCGACAAGGTGGCAGCTCTGGACCCACTATTGAAGAAGTTGATTAAGAACTTGCTAAGTGAATACTATTTTTTTAATACATTACTACTGTTAATTAATTATTGCAAAATATTGGATGATATCTGTTGCAATTATGACAACTGAAATCTTCTGTTGCATGTAGTATGTGCATTAGCAATGCAACTCCTTTTTTATCTCAGTGTAAAGTAATAAGTATTCTTATATATAACACAGTATGCAATACCAACATAGTTAGTCAACAAAATAATCTGTATGATTTTGTCTGTACTGTATTATGTCATTATATAGTTTAATTTTGTTTTTAAGAAACACCTTTCATCCACAAATTACATTTTAAAGGTATTAAAGCAGACATTTAATTTCAGGAAAAGTACTGCATTGTTCCTTTTGTAAAGCTGAACATTTAAAATTGTTTTCATATAATTGCGTGTATTTTGCTTGTAATTTTGTTAATATACTGTGTCTTTTTGGTGATTTTTATATATTGTTGCTTAATGTACAGTATCATATTAGTGTAAACTGTGTTTTACATTTTAATGAATAAAAATAAACACATTTAAGCAGTTTAACCTCTTGTTTAATTCATCTTTATTCTACCTTGCTTGATGTGTCATTTTGAGTAAAGTGTCATAATTCTCAGTCACTTGTATATCATATTAGCAAAATTAATAGCTGTGATAAACATTTTACTTGTATTTTTCTGTCTTTCTGCTTATTCCCACAGCCACTTCCTACTCTACAATCATCTGCTGGTACTGCAGTTTCAGAACTTACACATTTGCCTGTCACTTGCAAATGCTATTTAAAACAAATATGTTATAAGGCTGCATTGTGTGCATTTGCAGTGTAATCAAGTGATGCAGCACTGTTAATTGTATAAAAAGAAAAACAGTATGTTAGCATAAATATGTATTTTTGTCATTAAAGGTGACTTGTCGCTCAGACATAAAAAGCTGTATAATAAAACTCCTGTTCAAATTAAAAAAAAAAAAAAAAAA	Refseq >NM_001127675|Xenopus laevis heat shock 70kDa protein (hsp70), mRNA ATGGCAACCAAAGGAGTCGCAGTCGGCATTGACCTCGGCACTACCTACTCTTGCGTTGGTGTTTTCCAGCATGGTAAAGTAGAGATCATCGCTAATGACCAAGGGAATCGCACCACTCCCAGCTATGTGGCTTTCACAGACACAGAAAGGCTGATTGGCGATGCAGCCAAGAATCAAGTGGCCATGAACCCCCAGAATACAGTGTTTGATGCCAAGAGACTGATCGGGAGAAAGTTCAATGATCCTGTAGTGCAGTGTGACTTGAAGCACTGGCCGTTCCAAGTGGTGAGCGATGAGGGGAAGCCTAAGGTCAAAGTGGAGTATAAAGGAGAAGAGAAAAGCTTCTTCCCTGAGGAGATCTCCTCTATGGTGCTTACAAAGATGAAAGAGACAGCAGAAGCTTACCTGGGCCACCCTGTTACCAATGCTGTTATCACTGTGCCAGCCTACTTTAATGATTCCCAGAGACAGGCCACCAAGGATGCTGGTGTACTTGCAGGACTGAATATTTTGAGAATCATCAATGAGCCGACAGCAGCTGCTATTGCTTATGGCTTAGACAAAGGAGCCAGAGGGGAGCAAAATGTGCTTATTTTTGATTTGGGAGGCGGAACATTTGATGTCTCCATCCTTACTATCGATGATGGCATCTTTGAAGTGAAGGCAACAGCCGGCGACACTCATCTGGGTGGAGAAGACTTTGACAATCGTATGGTGAATCACTTTGTGGAGGAATTCAAGCGAAAACACAAGAAGGATATCGGTCAGAACAAAAGAGCTCTGAGGAGGCTGAGAACAGCCTGTGACCGAGCAAAGCGCACCCTGTCATCCAGCAGCCAGGCAAGCATTGAAATTGACTCCCTCTTTGAAGGTATTGACTTCTACACAGCCATCACCAGGGCCCGCTTTGAAGAACTGTGCTCTGACCTCTTCAGGGGTACCTTGGAACCTGTGGAAAAGGCTCTGAGAGATGCCAAGTTAGACAAATCTCAGATACACGAGATTGTCCTTGTGGGGGGTTCCACACGCATTCCTAAAGTGCAAAAGCTGCTTCAAGACTTCTTTAATGGCAGAGAGCTAAACAAGAGCATAAATCCTGATGAAGCTGTGGCATATGGAGCTGCTGTACAGGCTGCCATCCTAATGGGTGACAAATCAGAAAATGTGCAAGATTTACTTCTGTTGGATGTTGCACCTCTGTCACTGGGCTTGGAGACAGCAGGAGGAGTAATGACTGTGCTCATCAAGCGCAACACAACAATCCCAACCAAACAGACACAGTCCTTCACCACATACTCTGACAATCAGCCTGGGGTGCTTATCCAGGTGTTTGAGGGAGAGAGGGCTATGACCAAAGACAATAACCTTTTGGGGAAATTTGAGTTAAGTGGAATCCCCCCTGCTCCCAGAGGAGTACCTCAGATTGAAGTCACCTTTGACATTGATGCTAATGGCATACTAAATGTGTCTGCTGTGGAAAAGAGCTCTGGTAAACAGAATAAGATCACAATCACAAATGACAAAGGGCGGCTGAGTAAAGAGGACATTGAAAAGATGGTACAGGAGGCAGAAAAGTACAAGGCTGATGATGATGCCCAAAGAGAAAGGGTTGATGCCAAAAACGCACTAGAATCCTATGCATTCAACTTAAAAAGTATGGTGGAAGATGAAAACGTGAAAGGCAAGATTAGTGATGAAGACAAGAGAACAATTTCAGAGAAGTGCACACAGGTCATTTCCTGGCTGGAGAATAATCAGCTGGCTGAGAAAGAAGAGTATGCCTTCCAGCAGAAAGATCTAGAAAAAGTATGCCAGCCCATTATTACAAAACTGTATCAAGGCGGTGTGCCAGGAGGTGTGCCAGGAGGCATGCCAGGTTCTAGCTGTGGTGCTCAGGCCCGACAAGGTGGCAACTCGGGTCCAACTATAGAAGAAGTTGACTAA
Protein		Refseq >NP_001106370|heat shock 70kDa protein [Xenopus (Silurana) tropicalis] MASKGVAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDLKHWPFQVVSDHGKPKVKVEFKGEEKTFFPEEISSMVLIKMKETAEAYLGHAVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGTRGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFMEEFKRKHKKDISQNKRALRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKSQIDEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKEDIEKMVQEAERYKADDDAQREKIDAKNSLESYAFNLKSMVEDENMKGKISEGDKRIISEKCTQIISWLENNQLAEKDEYAFQQKELERVCQPIITKLYQGSMPGSMPGSSCGAQARQGGSSGPTIEEVD	Refseq >NP_001121147|heat shock 70 kDa protein [Xenopus laevis] MATKGVAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQCDLKHWPFQVVSDEGKPKVKVEYKGEEKSFFPEEISSMVLTKMKETAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVLAGLNILRIINEPTAAAIAYGLDKGARGEQNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDIGQNKRALRRLRTACDRAKRTLSSSSQASIEIDSLFEGIDFYTAITRARFEELCSDLFRGTLEPVEKALRDAKLDKSQIHEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQSFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKEDIEKMVQEAEKYKADDDAQRERVDAKNALESYAFNLKSMVEDENVKGKISDEDKRTISEKCTQVISWLENNQLAEKEEYAFQQKDLEKVCQPIITKLYQGGVPGGVPGGMPGSSCGAQARQGGNSGPTIEEVD UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.39924 [+] Str.72982 Str.83688	[+] Xl.21493
Unigene EST Profile		EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish		ZFIN	hsp70

Publications
First:		Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals. [EMBO J 1982]
Most recent:		The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum associated degradation of the epithelial sodium channel. [J Biol Chem 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		ATP binding
Biological:
Cellular Component:
EC:
KOG:		[O] Molecular chaperones HSP70/HSC70, HSP70 superfamily

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.39924.3.A1_a_at [+] Str.39924.2.S1_at	Xl.21493.1.S1_at
Affymetrix 2.0			Xl2.21493.1.S1_at

Symbol legend[+]

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   - Literature Or Expression Images