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Summary Expression Phenotypes Gene Literature (52) GO Terms (5) Nucleotides (60) Proteins (36) Interactants (120) Wiki
XB-GENEPAGE-5824075

Papers associated with slc6a1



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Flux coupling, not specificity, shapes the transport and phylogeny of SLC6 glycine transporters., Le Guellec B, Rousseau F, Bied M, Supplisson S., Proc Natl Acad Sci U S A. October 11, 2022; 119 (41): e2205874119.                                              

The Lepidopteran KAAT1 and CAATCH1: Orthologs to Understand Structure-Function Relationships in Mammalian SLC6 Transporters., Castagna M, Cinquetti R, Verri T, Vacca F, Giovanola M, Barca A, Romanazzi T, Roseti C, Galli A, Bossi E., Neurochem Res. January 1, 2022; 47 (1): 111-126.          

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB, Willsey HR, Xu Y, Xu Y, Mei Y, Dea J, Wang S, Curtis C, Sempou E, Khokha MK, Chi NC, Willsey AJ, Fisch KM, Ideker T., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.            

Evidence for a Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters., Willford SL, Anderson CM, Spencer SR, Eskandari S., J Membr Biol. August 1, 2015; 248 (4): 795-810.

Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue., Omoto JJ, Maestas MJ, Rahnama-Vaghef A, Choi YE, Salto G, Sanchez RV, Anderson CM, Eskandari S., J Membr Biol. December 1, 2012; 245 (12): 841-57.                  

An inverse relationship links temperature and substrate apparent affinity in the ion-coupled cotransporters rGAT1 and KAAT1., Peres A, Vollero A, Margheritis E, D'Antoni F, Bossi E., Int J Mol Sci. November 22, 2012; 13 (12): 15565-74.      

Using lithium to probe sequential cation interactions with GAT1., Meinild AK, Forster IC., Am J Physiol Cell Physiol. June 1, 2012; 302 (11): C1661-75.

Pre-steady-state and reverse transport currents in the GABA transporter GAT1., Cherubino F, Bertram S, Bossi E, Peres A., Am J Physiol Cell Physiol. April 15, 2012; 302 (8): C1096-108.

An integrated field-effect microdevice for monitoring membrane transport in Xenopus laevis oocytes via lateral proton diffusion., Schaffhauser DF, Patti M, Goda T, Miyahara Y, Forster IC, Dittrich PS., PLoS One. January 1, 2012; 7 (7): e39238.          

Inhibition of Activity of GABA Transporter GAT1 by δ-Opioid Receptor., Pu L, Xu N, Xia P, Gu Q, Ren S, Fucke T, Pei G, Schwarz W., Evid Based Complement Alternat Med. January 1, 2012; 2012 818451.              

GABA reverse transport by the neuronal cotransporter GAT1: influence of internal chloride depletion., Bertram S, Cherubino F, Bossi E, Castagna M, Peres A., Am J Physiol Cell Physiol. November 1, 2011; 301 (5): C1064-73.

Passive water permeability of some wild type and mutagenized amino acid cotransporters of the SLC6/NSS family expressed in Xenopus laevis oocytes., Santacroce M, Castagna M, Sacchi VF., Comp Biochem Physiol A Mol Integr Physiol. August 1, 2010; 156 (4): 509-17.

Inhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction., Matthews E, Rahnama-Vaghef A, Eskandari S., Neurochem Int. December 1, 2009; 55 (8): 732-40.

Turnover rate of the gamma-aminobutyric acid transporter GAT1., Gonzales AL, Lee W, Spencer SR, Oropeza RA, Chapman JV, Ku JY, Eskandari S., J Membr Biol. December 1, 2007; 220 (1-3): 33-51.

N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a., Wiles AL, Pearlman RJ, Rosvall M, Aubrey KR, Vandenberg RJ., J Neurochem. November 1, 2006; 99 (3): 781-6.

The role of early lineage in GABAergic and glutamatergic cell fate determination in Xenopus laevis., Li M, Sipe CW, Hoke K, August LL, Wright MA, Saha MS., J Comp Neurol. April 20, 2006; 495 (6): 645-57.                    

AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana., Meyer A, Eskandari S, Grallath S, Rentsch D., J Biol Chem. March 17, 2006; 281 (11): 7197-204.

Identification and selective inhibition of the channel mode of the neuronal GABA transporter 1., Krause S, Schwarz W., Mol Pharmacol. December 1, 2005; 68 (6): 1728-35.

Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells., Su TZ, Feng MR, Weber ML., J Pharmacol Exp Ther. June 1, 2005; 313 (3): 1406-15.

Expression and transport function of the glutamate transporter EAAC1 in Xenopus oocytes is regulated by syntaxin 1A., Zhu Y, Fei J, Schwarz W., J Neurosci Res. February 15, 2005; 79 (4): 503-8.

Relations between substrate affinities and charge equilibration rates in the rat GABA cotransporter GAT1., Soragna A, Bossi E, Giovannardi S, Pisani R, Peres A., J Physiol. January 15, 2005; 562 (Pt 2): 333-45.

Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4)., Karakossian MH, Spencer SR, Gomez AQ, Padilla OR, Sacher A, Loo DD, Nelson N, Eskandari S., J Membr Biol. January 1, 2005; 203 (2): 65-82.

Antiepileptic action induced by a combination of vigabatrin and tiagabine., Fueta Y, Kunugita N, Schwarz W., Neuroscience. January 1, 2005; 132 (2): 335-45.

Intracellular domains of a rat brain GABA transporter that govern transport., Hansra N, Arya S, Quick MW., J Neurosci. April 21, 2004; 24 (16): 4082-7.

Modulation of Na(+),K(+) pumping and neurotransmitter uptake by beta-amyloid., Gu QB, Zhao JX, Fei J, Schwarz W., Neuroscience. January 1, 2004; 126 (1): 61-7.

Syntaxin 1A inhibits GABA flux, efflux, and exchange mediated by the rat brain GABA transporter GAT1., Wang D, Deken SL, Whitworth TL, Quick MW., Mol Pharmacol. October 1, 2003; 64 (4): 905-13.

The anticonvulsant valproate increases the turnover rate of gamma-aminobutyric acid transporters., Whitlow RD, Sacher A, Loo DD, Nelson N, Eskandari S., J Biol Chem. May 16, 2003; 278 (20): 17716-26.

Effect of sodium lithium and proton concentrations on the electrophysiological properties of the four mouse GABA transporters expressed in Xenopus oocytes., Grossman TR, Nelson N., Neurochem Int. January 1, 2003; 43 (4-5): 431-43.

Down-regulation of GABA-transporter function by hippocampal translation products: its possible role in epilepsy., Fueta Y, Vasilets LA, Takeda K, Kawamura M, Schwarz W., Neuroscience. January 1, 2003; 118 (2): 371-8.

K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity., Liu Z, Stevens BR, Feldman DH, Hediger MA, Harvey WR., J Exp Biol. January 1, 2003; 206 (Pt 2): 245-54.

Differential effect of pH on sodium binding by the various GABA transporters expressed in Xenopus oocytes., Grossman TR, Nelson N., FEBS Lett. September 11, 2002; 527 (1-3): 125-32.

Transport of L-carnitine in isolated cerebral cortex neurons., Wawrzeńczyk A, Sacher A, Mac M, Nałecz MJ, Nałecz KA., Eur J Biochem. April 1, 2001; 268 (7): 2091-8.

Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution., Horton N, Quick MW., Mol Membr Biol. January 1, 2001; 18 (1): 39-44.

Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1., Loo DD, Eskandari S, Boorer KJ, Sarkar HK, Wright EM., J Biol Chem. December 1, 2000; 275 (48): 37414-22.

Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A., Deken SL, Beckman ML, Boos L, Quick MW., Nat Neurosci. October 1, 2000; 3 (10): 998-1003.

An intermediate state of the gamma-aminobutyric acid transporter GAT1 revealed by simultaneous voltage clamp and fluorescence., Li M, Farley RA, Lester HA., J Gen Physiol. April 1, 2000; 115 (4): 491-508.                              

Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs., Eckstein-Ludwig U, Fei J, Schwarz W., Br J Pharmacol. September 1, 1999; 128 (1): 92-102.

GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model., Hilgemann DW, Lu CC., J Gen Physiol. September 1, 1999; 114 (3): 459-75.                                

GAT1 (GABA:Na+:Cl-) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches., Lu CC, Hilgemann DW., J Gen Physiol. September 1, 1999; 114 (3): 445-57.                  

GAT1 (GABA:Na+:Cl-) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches., Lu CC, Hilgemann DW., J Gen Physiol. September 1, 1999; 114 (3): 429-44.                        

Passive water and ion transport by cotransporters., Loo DD, Hirayama BA, Meinild AK, Chandy G, Zeuthen T, Wright EM., J Physiol. July 1, 1999; 518 ( Pt 1) 195-202.

Effect of mutation of glycosylation sites on the Na+ dependence of steady-state and transient currents generated by the neuronal GABA transporter., Liu Y, Eckstein-Ludwig U, Fei J, Schwarz W., Biochim Biophys Acta. December 9, 1998; 1415 (1): 246-54.

Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation., Yu N, Cao Y, Mager S, Lester HA., FEBS Lett. April 17, 1998; 426 (2): 174-8.

Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1., Quick MW, Corey JL, Davidson N, Lester HA., J Neurosci. May 1, 1997; 17 (9): 2967-79.

Ion binding and permeation at the GABA transporter GAT1., Mager S, Kleinberger-Doron N, Keshet GI, Davidson N, Kanner BI, Lester HA., J Neurosci. September 1, 1996; 16 (17): 5405-14.

Short external loops as potential substrate binding site of gamma-aminobutyric acid transporters., Tamura S, Nelson H, Tamura A, Nelson N., J Biol Chem. December 1, 1995; 270 (48): 28712-5.

Membrane transport mechanisms probed by capacitance measurements with megahertz voltage clamp., Lu CC, Kabakov A, Markin VS, Mager S, Frazier GA, Hilgemann DW., Proc Natl Acad Sci U S A. November 21, 1995; 92 (24): 11220-4.

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter., Corey JL, Davidson N, Lester HA, Brecha N, Quick MW., J Biol Chem. May 20, 1994; 269 (20): 14759-67.

Phorbol ester-induced inhibition of GABA uptake by synaptosomes and by Xenopus oocytes expressing GABA transporter (GAT1)., Osawa I, Saito N, Koga T, Tanaka C., Neurosci Res. May 1, 1994; 19 (3): 287-93.

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes., Mager S, Naeve J, Quick M, Labarca C, Davidson N, Lester HA., Neuron. February 1, 1993; 10 (2): 177-88.

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