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Summary Expression Phenotypes Gene Literature (34) GO Terms (4) Nucleotides (88) Proteins (60) Interactants (42) Wiki
XB-GENEPAGE-948181

Papers associated with slc6a9



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The Lepidopteran KAAT1 and CAATCH1: Orthologs to Understand Structure-Function Relationships in Mammalian SLC6 Transporters., Castagna M, Cinquetti R, Verri T, Vacca F, Giovanola M, Barca A, Romanazzi T, Roseti C, Galli A, Bossi E., Neurochem Res. January 1, 2022; 47 (1): 111-126.          


Modulation of Glycinergic Neurotransmission may Contribute to the Analgesic Effects of Propacetamol., Barsch L, Werdehausen R, Leffler A, Eulenburg V., Biomolecules. March 25, 2021; 11 (4):                             


A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Sheipouri D, Gallagher CI, Shimmon S, Rawling T, Vandenberg RJ., Biomolecules. November 30, 2020; 10 (12):                                                     


GlyT1 encephalopathy: Characterization of presumably disease causing GlyT1 mutations., Hauf K, Barsch L, Bauer D, Buchert R, Armbruster A, Frauenfeld L, Grasshoff U, Eulenburg V., Neurochem Int. October 1, 2020; 139 104813.


Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors., Amberg W, Lange UEW, Ochse M, Pohlki F, Behl B, Relo AL, Hornberger W, Hoft C, Mezler M, Sydor J, Wang Y, Zhao H, Brewer JT, Dietrich J, Li H, Akritopoulou-Zanze I, Lao Y, Hannick SM, Ku YY, Vasudevan A., J Med Chem. September 13, 2018; 61 (17): 7503-7524.


De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors., Wang Y, Zhao H, Brewer JT, Li H, Lao Y, Amberg W, Behl B, Akritopoulou-Zanze I, Dietrich J, Lange UEW, Pohlki F, Hoft C, Hornberger W, Djuric SW, Sydor J, Mezler M, Relo AL, Vasudevan A., J Med Chem. September 13, 2018; 61 (17): 7486-7502.


Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2., Mostyn SN, Carland JE, Shimmon S, Ryan RM, Rawling T, Vandenberg RJ., ACS Chem Neurosci. September 20, 2017; 8 (9): 1949-1959.


Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina., Bessodes N, Parain K, Bronchain O, Bellefroid EJ, Perron M., Neural Dev. September 1, 2017; 12 (1): 16.                


Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2., Subramanian N, Scopelitti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ., PLoS One. January 1, 2016; 11 (6): e0157583.            


The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain., Werdehausen R, Mittnacht S, Bee LA, Minett MS, Armbruster A, Bauer I, Wood JN, Hermanns H, Eulenburg V., Pain. September 1, 2015; 156 (9): 1647-1659.                


Glycine transporters GlyT1 and GlyT2 are differentially modulated by glycogen synthase kinase 3β., Jiménez E, Núñez E, Ibáñez I, Zafra F, Aragón C, Giménez C., Neuropharmacology. February 1, 2015; 89 245-54.


Oleoyl-L-carnitine inhibits glycine transport by GlyT2., Carland JE, Mansfield RE, Ryan RM, Vandenberg RJ., Br J Pharmacol. February 1, 2013; 168 (4): 891-902.


Transport activities and expression patterns of glycine transporters 1 and 2 in the developing murine brain stem and spinal cord., Lall D, Armbruster A, Ruffert K, Betz H, Eulenburg V., Biochem Biophys Res Commun. July 13, 2012; 423 (4): 661-6.


An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling., Pérez-Siles G, Núñez E, Morreale A, Jiménez E, Leo-Macías A, Pita G, Cherubino F, Sangaletti R, Bossi E, Ortíz AR, Aragón C, López-Corcuera B., Biochem J. March 1, 2012; 442 (2): 323-34.


Lidocaine metabolites inhibit glycine transporter 1: a novel mechanism for the analgesic action of systemic lidocaine?, Werdehausen R, Kremer D, Brandenburger T, Schlösser L, Jadasz J, Küry P, Bauer I, Aragón C, Eulenburg V, Hermanns H., Anesthesiology. January 1, 2012; 116 (1): 147-58.


Transient currents in the glycine cotransporter GlyT1 reveal different steps in transport mechanism., Cherubino F, Bossi E, Miszner A, Ghezzi C, Peres A., J Mol Neurosci. June 1, 2010; 41 (2): 243-51.


Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport., Edington AR, McKinzie AA, Reynolds AJ, Kassiou M, Ryan RM, Vandenberg RJ., J Biol Chem. December 25, 2009; 284 (52): 36424-36430.


Modulation of glutamate and glycine transporters by niflumic, flufenamic and mefenamic acids., Habjan S, Vandenberg RJ., Neurochem Res. October 1, 2009; 34 (10): 1738-47.


Inhibitors of GlyT1 affect glycine transport via discrete binding sites., Mezler M, Hornberger W, Mueller R, Schmidt M, Amberg MS, Braje W, Ochse M, Schoemaker H, Behl B, Schoemaker H, Behl B., Mol Pharmacol. December 1, 2008; 74 (6): 1705-15.


Expression patterns of glycine transporters (xGlyT1, xGlyT2, and xVIAAT) in Xenopus laevis during early development., Wester MR, Teasley DC, Byers SL, Saha MS., Gene Expr Patterns. April 1, 2008; 8 (4): 261-70.              


The contribution of the NMDA receptor glycine site to rhythm generation during fictive swimming in Xenopus laevis tadpoles., Issberner JP, Sillar KT., Eur J Neurosci. November 1, 2007; 26 (9): 2556-64.


Molecular basis for substrate discrimination by glycine transporters., Vandenberg RJ, Shaddick K, Ju P., J Biol Chem. May 11, 2007; 282 (19): 14447-53.


N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a., Wiles AL, Pearlman RJ, Rosvall M, Aubrey KR, Vandenberg RJ., J Neurochem. November 1, 2006; 99 (3): 781-6.


The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS., Cui WW, Low SE, Hirata H, Saint-Amant L, Geisler R, Hume RI, Kuwada JY., J Neurosci. July 13, 2005; 25 (28): 6610-20.


Zn2+ inhibits glycine transport by glycine transporter subtype 1b., Ju P, Aubrey KR, Vandenberg RJ., J Biol Chem. May 28, 2004; 279 (22): 22983-91.


Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a., Pearlman RJ, Aubrey KR, Vandenberg RJ., J Neurochem. February 1, 2003; 84 (3): 592-601.


N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport., Aubrey KR, Vandenberg RJ., Br J Pharmacol. December 1, 2001; 134 (7): 1429-36.


The glial and the neuronal glycine transporters differ in their reactivity to sulfhydryl reagents., Roux MJ, Martinez-Maza R, Le Goff A, Lopez-Corcuera B, Aragon C, Supplisson S., J Biol Chem. May 25, 2001; 276 (21): 17699-705.


Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytes., Horiuchi M, Nicke A, Gomeza J, Aschrafi A, Schmalzing G, Betz H., Proc Natl Acad Sci U S A. February 13, 2001; 98 (4): 1448-53.


Molecular basis for proton regulation of glycine transport by glycine transporter subtype 1b., Aubrey KR, Mitrovic AD, Vandenberg RJ., Mol Pharmacol. July 1, 2000; 58 (1): 129-35.


Neuronal and glial glycine transporters have different stoichiometries., Roux MJ, Supplisson S., Neuron. February 1, 2000; 25 (2): 373-83.


Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes., Supplisson S, Bergman C., J Neurosci. June 15, 1997; 17 (12): 4580-90.


Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features., Liu QR, López-Corcuera B, Mandiyan S, Nelson H, Nelson N., J Biol Chem. October 25, 1993; 268 (30): 22802-8.


Cloning, expression, and localization of a rat brain high-affinity glycine transporter., Guastella J, Brecha N, Weigmann C, Lester HA, Davidson N., Proc Natl Acad Sci U S A. August 1, 1992; 89 (15): 7189-93.

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