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DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation. , Kingsley G, Skagia A, Passaretti P, Fernandez-Cuesta C, Reynolds-Winczura A, Koscielniak K, Gambus A., Nucleic Acids Res. October 13, 2023; 51 (18): 9748-9763.
A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation. , Valverde JM, Dubra G, Phillips M, Haider A, Elena-Real C, Fournet A, Alghoul E, Chahar D, Andrés-Sanchez N, Paloni M, Bernadó P, van Mierlo G, Vermeulen M, van den Toorn H, Heck AJR, Constantinou A, Barducci A, Ghosh K, Sibille N, Knipscheer P , Krasinska L, Fisher D , Altelaar M., Nat Commun. October 9, 2023; 14 (1): 6316.
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. , Jones MJK, Gelot C, Munk S, Koren A, Kawasoe Y, George KA, Santos RE, Olsen JV, McCarroll SA, Frattini MG, Takahashi TS, Jallepalli PV., Mol Cell. February 4, 2021; 81 (3): 426-441.e8.
Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei. , Okada T, Okabe G, Tak YS, Mimura S, Takisawa H, Kubota Y., Genes Cells. February 1, 2018; 23 (2): 94-104.
An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7. , Perez-Arnaiz P, Bruck I, Colbert MK, Kaplan DL., Nucleic Acids Res. July 7, 2017; 45 (12): 7261-7275.
Reversal of DDK-Mediated MCM Phosphorylation by Rif1- PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/ Chk1. , Alver RC, Chadha GS, Gillespie PJ, Blow JJ ., Cell Rep. March 7, 2017; 18 (10): 2508-2520.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS, Gambus A, Gillespie PJ, Blow JJ ., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae. , Brandão LN, Ferguson R, Santoro I, Jinks-Robertson S, Sclafani RA., Genetics. August 1, 2014; 197 (4): 1111-22.
The role of Dbf4/ Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control. , Tsuji T, Lau E, Chiang GG, Jiang W., Mol Cell. December 26, 2008; 32 (6): 862-9.
Cdc7- Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. , Takahashi TS, Basu A, Bermudez V, Hurwitz J , Walter JC ., Genes Dev. July 15, 2008; 22 (14): 1894-905.
Xenopus CDC7/ DRF1 complex is required for the initiation of DNA replication. , Silva T, Bradley RH, Gao Y, Coue M., J Biol Chem. April 28, 2006; 281 (17): 11569-76.
Cdc7- Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication. , Takahashi TS, Walter JC ., Genes Dev. October 1, 2005; 19 (19): 2295-300.
Frodo proteins: modulators of Wnt signaling in vertebrate development. , Brott BK, Sokol SY ., Differentiation. September 1, 2005; 73 (7): 323-9.
A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development. , Brott BK, Sokol SY ., Dev Cell. May 1, 2005; 8 (5): 703-15.
A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication. , Jares P, Luciani MG, Blow JJ ., BMC Mol Biol. June 28, 2004; 5 5.
Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts. , Duncker BP, Brown GW., Mutat Res. November 27, 2003; 532 (1-2): 21-7.
Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest. , Yanow SK, Gold DA, Yoo HY, Dunphy WG ., J Biol Chem. October 17, 2003; 278 (42): 41083-92.
Identification and characterization of a Xenopus homolog of Dbf4, a regulatory subunit of the Cdc7 protein kinase required for the initiation of DNA replication. , Furukohri A, Sato N, Masai H, Arai K, Sugino A, Waga S., J Biochem. September 1, 2003; 134 (3): 447-57.
Cyclin-dependent kinases and S phase control in mammalian cells. , Woo RA, Poon RY., Cell Cycle. January 1, 2003; 2 (4): 316-24.
Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. , Chou DM, Petersen P, Walter JC , Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.
Protein kinase A is required for chromosomal DNA replication. , Costanzo V, Avvedimento EV, Gottesman ME, Gautier J , Grieco D., Curr Biol. August 26, 1999; 9 (16): 903-6.