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Summary Expression Phenotypes Gene Literature (11) GO Terms (13) Nucleotides (46) Proteins (30) Interactants (320) Wiki
XB-GENEPAGE-952684

Papers associated with rnf43



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R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  


The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                


Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                


Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification., Reis AH, Sokol SY., Sci Rep. June 28, 2021; 11 (1): 13433.            


TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           


The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               


RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6., Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Vleminckx K, Barker N, Kayserili H, Reversade B., Nature. May 1, 2018; 557 (7706): 564-569.  


High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  


The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane., Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M., Sci Signal. September 8, 2015; 8 (393): ra90.


The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength., de Lau W, Peng WC, Gros P, Clevers H., Genes Dev. February 15, 2014; 28 (4): 305-16.          


Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin., Zebisch M, Xu Y, Xu Y, Krastev C, MacDonald BT, Chen M, Gilbert RJ, He X, Jones EY., Nat Commun. January 1, 2013; 4 2787.              

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