| Monarch Ortholog Phenotypes
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Human (27 sources):
Abnormal circulating enzyme concentration,
Abnormal pancreatic duct morphology,
Anorexia,
Ascites,
Biliary hyperplasia,
Biliary tract obstruction,
Cholelithiasis,
Cholesterol gallstones,
Chronic pancreatitis,
Cyst of the ductus choledochus,
Decreased urine output,
Elevated circulating hepatic transaminase concentration,
Episodic abdominal pain,
Fever,
Gastrointestinal dysmotility,
Hypertriglyceridemia,
Jaundice,
Leukemia,
Lymphoma,
Nausea and vomiting,
Pancreas divisum,
Pancreatic pseudocyst,
Respiratory distress,
Seizure,
Sphincter of Oddi dyskinesia,
Systemic lupus erythematosus,
Type I diabetes mellitus
[+]
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Mouse (3 sources):
abnormal vitreous body morphology,
enlarged cecum,
increased susceptibility to induced pancreatitis
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.