nfasc Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (147)

Interactants (28)

XB-GENEPAGE-922968

Gene Symbol: nfasc Gene Name: neurofascin

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nfasc assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): 11 pairs of ribs, Aggressive behavior, Anxiety, Ataxia, Babinski sign, Cerebellar atrophy, Cleft palate, Decreased fetal movement, Decreased nerve conduction velocity, Delayed ability to walk, Drug-induced agranulocytosis, Dysarthria, Dysdiadochokinesis, Dysmetria, Failure to thrive, Feeding difficulties, Generalized hypotonia, Global developmental delay, Glossoptosis, Hyperextensibility of the finger joints, Hyperreflexia, Hypertelorism, Hyporeflexia, Intention tremor, Microcephaly, Myoclonus, Prominent nasal bridge, Respiratory insufficiency, Seizure, Spasticity, Wide nasal bridge [+]
Mouse (17 sources): abnormal Purkinje cell morphology, abnormal action potential, abnormal axon initial segment morphology, abnormal axon morphology, abnormal limb posture, abnormal motor capabilities/coordination/movement, abnormal oligodendrocyte physiology, abnormal paranodal axoglial junction morphology, abnormal paranode morphology, abnormal sciatic nerve morphology, abnormal synapse morphology, decreased locomotor activity, impaired ability to fire action potentials, impaired balance, increased circulating glucose level, nervous system phenotype, postnatal lethality, complete penetrance [+]
View all ortholog results at Monarch