| Monarch Ortholog Phenotypes
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Human (30 sources):
Abnormal foot morphology,
Abnormal form of the vertebral bodies,
Abnormality of the knee,
Arthropathy,
Camptodactyly of finger,
Coxa vara,
Decreased cervical spine mobility,
Difficulty walking,
Enlarged epiphyses,
Enlarged interphalangeal joints,
Enlarged metacarpophalangeal joints,
Enlargement of the proximal femoral epiphysis,
Flattened epiphysis,
Gait disturbance,
Genu varum,
Joint contracture of the hand,
Joint stiffness,
Joint swelling,
Kyphoscoliosis,
Kyphosis,
Metaphyseal widening,
Methylmalonic acidemia,
Muscle weakness,
Osteoarthritis,
Osteoporosis,
Platyspondyly,
Sclerotic vertebral endplates,
Scoliosis,
Short stature,
Waddling gait
[+]
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Mouse (8 sources):
abnormal involution of the mammary gland,
abnormal mammary duct terminal end bud morphology,
abnormal mammary gland duct morphology,
abnormal mammary gland morphology,
increased mammary adenocarcinoma incidence,
increased metastatic potential,
mammary gland duct hyperplasia,
no abnormal phenotype detected
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.