fadd Phenotypes

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Phenotypes

Gene Literature (11)

Nucleotides (116)

Interactants (186)

XB-GENEPAGE-1001299

Gene Symbol: fadd Gene Name: Fas associated via death domain

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
increased apoptosis in embryo (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + Hsa.FADD (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Autoimmune antibody positivity, Cerebral atrophy, Decreased liver function, Encephalopathy, Hepatic fibrosis, Howell-Jolly bodies, Pulmonary artery atresia, Recurrent infections, Seizure, Ventricular septal defect
Mouse (44 sources): abnormal T cell proliferation, abnormal T cell subpopulation ratio, abnormal bone marrow cell morphology/development, abnormal cecum morphology, abnormal colon morphology, abnormal embryo size, abnormal enterocyte physiology, abnormal enterocyte proliferation, abnormal erythrocyte cell number, abnormal forebrain development, abnormal hindbrain development, abnormal intestinal mucosa morphology, abnormal midbrain development, abnormal myocardium layer morphology, abnormal oligodendrocyte apoptosis, abnormal thymocyte apoptosis, abnormal uterus morphology, cecum inflammation, crypts of Lieberkuhn abscesses, decreased Paneth cell number, decreased activated T cell number, decreased bone marrow cell number, decreased bone mineral content, decreased embryo size, decreased fibroblast apoptosis, decreased lean body mass, decreased sensitivity to induced cell death, decreased single-positive T cell number, decreased susceptibility to experimental autoimmune encephalomyelitis, embryonic growth retardation, embryonic lethality, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, enlarged lymph nodes, immune system phenotype, increased enterocyte apoptosis, increased susceptibility to parasitic infection, increased total body fat amount, intestinal ulcer, nervous system phenotype, postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, thin myocardium, trabecula carnea hypoplasia [+]
View all ortholog results at Monarch