| Monarch Ortholog Phenotypes
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Human (2 sources):
Hypercoagulability,
Recurrent deep vein thrombosis
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Mouse (38 sources):
abnormal active avoidance behavior,
abnormal acute phase protein level,
abnormal contextual conditioning behavior,
abnormal cued conditioning behavior,
abnormal cytokine level,
abnormal microglial cell physiology,
abnormal motor learning,
abnormal response to CNS ischemic injury,
abnormal susceptibility to Coronaviridae infection,
absent long term depression,
behavior/neurological phenotype,
cardiac interstitial fibrosis,
chronic joint inflammation,
decreased angiogenesis,
decreased anxiety-related response,
decreased cerebral infarct size,
decreased dopamine level,
decreased exploration in new environment,
decreased retina apoptosis,
decreased spleen weight,
decreased susceptibility to induced choroidal neovascularization,
decreased susceptibility to induced retina damage,
decreased ventricle muscle contractility,
decreased vertical activity,
growth/size/body region phenotype,
immune system phenotype,
impaired behavioral response to morphine,
impaired conditioned place preference behavior,
impaired synaptic plasticity,
increased macrophage cell number,
increased susceptibility to Coronaviridae infection induced morbidity/mortality,
increased susceptibility to induced thrombosis,
muscle phenotype,
pulmonary alveolar hemorrhage,
pulmonary interstitial fibrosis,
reduced long term potentiation,
reduced thrombolysis,
reproductive system phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.