rictor Phenotypes

Summary

Expression

Phenotypes

Gene Literature (3)

XB-GENEPAGE-1013104

Gene Symbol: rictor Gene Name: RPTOR independent companion of MTOR, complex 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: rictor assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (40 sources): abnormal double-negative T cell morphology, abnormal pancreatic beta cell physiology, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placental labyrinth vasculature morphology, decreased DN1 thymic pro-T cell number, decreased DN2 thymocyte number, decreased DN3 thymocyte number, decreased DN4 thymocyte number, decreased T cell proliferation, decreased cell proliferation, decreased double-positive T cell number, decreased embryo size, decreased insulin secretion, decreased pancreatic beta cell mass, decreased pancreatic beta cell proliferation, decreased single-positive T cell number, decreased thymus weight, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, hematopoietic system phenotype, immune system phenotype, improved glucose tolerance, increased body length, increased bone mineral content, increased circulating insulin-like growth factor I level, increased double-negative T cell number, increased epididymal fat pad weight, increased heart weight, increased kidney weight, increased lean body mass, increased liver weight, increased pancreas weight, increased spleen weight, increased susceptibility to weight gain, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, macrovesicular hepatic steatosis, muscle phenotype, thick placenta labyrinth [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (40 sources): abnormal double-negative T cell morphology, abnormal pancreatic beta cell physiology, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placental labyrinth vasculature morphology, decreased DN1 thymic pro-T cell number, decreased DN2 thymocyte number, decreased DN3 thymocyte number, decreased DN4 thymocyte number, decreased T cell proliferation, [+]