Monarch Ortholog Phenotypes
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Human (19 sources):
Cerebral hemorrhage,
Choroidal hemangioma,
Cognitive impairment,
Episodic vomiting,
Focal T2 hyperintense brainstem lesion,
Focal T2 hypointense brainstem lesion,
Headache,
Hemangioma,
Increased intracranial pressure,
Meningioma,
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Mouse (60 sources):
CNS inflammation,
abnormal angiogenesis,
abnormal artery development,
abnormal astrocyte morphology,
abnormal atrioventricular cushion morphology,
abnormal blood-brain barrier function,
abnormal brain vasculature morphology,
abnormal cardiac jelly morphology,
abnormal cardinal vein morphology,
abnormal choroid plexus morphology,
abnormal developmental vascular remodeling,
abnormal dorsal aorta morphology,
abnormal first pharyngeal arch artery morphology,
abnormal first pharyngeal arch morphology,
abnormal heart development,
abnormal heart tube morphology,
abnormal pericyte morphology,
abnormal pharyngeal arch artery morphology,
abnormal placental labyrinth vasculature morphology,
abnormal retina vasculature morphology,
abnormal second pharyngeal arch artery morphology,
abnormal second pharyngeal arch morphology,
abnormal sinus venosus morphology,
abnormal somite development,
abnormal third pharyngeal arch artery morphology,
abnormal third pharyngeal arch morphology,
abnormal vascular branching morphogenesis,
abnormal vascular endothelial cell development,
abnormal vascular endothelial cell morphology,
abnormal vascular smooth muscle morphology,
abnormal vasculogenesis,
abnormal vitelline vascular remodeling,
abnormal vitelline vasculature morphology,
absent vitelline blood vessels,
cerebellum hemorrhage,
decreased angiogenesis,
dilated aortic sac,
dilated dorsal aorta,
dilated vasculature,
disorganized extraembryonic tissue,
embryonic growth arrest,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
enlarged heart atrium,
failure of heart looping,
lethality throughout fetal growth and development, complete penetrance,
microgliosis,
no abnormal phenotype detected,
pale placenta,
pale yolk sac,
pericardial edema,
poor circulation,
postnatal lethality,
postnatal lethality, complete penetrance,
premature death,
prenatal lethality, complete penetrance,
short forehead,
skin hemorrhage,
thin myocardium,
thin ventricular wall
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View all ortholog results at Monarch
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