cdk5r1 Phenotypes

Phenotypes

XB-GENEPAGE-22167144

Gene Symbol: cdk5r1 Gene Name: cyclin-dependent kinase 5, regulatory subunit 1 (p35)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cdk5r1 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (36 sources): abnormal axon extension, abnormal behavioral response to xenobiotic, abnormal cerebellar molecular layer, abnormal cerebral cortex morphology, abnormal cerebral cortex pyramidal cell morphology, abnormal dentate gyrus morphology, abnormal excitatory postsynaptic potential, abnormal forebrain development, abnormal hippocampus granule cell morphology, abnormal hippocampus layer morphology, abnormal hippocampus pyramidal cell morphology, abnormal innervation, abnormal long term depression, abnormal olfactory bulb development, abnormal physiological response to xenobiotic, abnormal sensitization to xenobiotic, abnormal spatial learning, abnormal stratification in cerebral cortex, abnormal subplate morphology, absent long term depression, decreased corpus callosum size, decreased striatum size, delaminated Purkinje cell layer, ectopic Purkinje cell, ectopic cerebellar granule cells, impaired synaptic plasticity, increased cellular glucose import, increased serotonin level, increased susceptibility to pharmacologically induced seizures, increased thermal nociceptive threshold, nervous system phenotype, premature death, reduced long term depression, reduced long term potentiation, slow extinction of fear memory, thin cortical plate [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (36 sources): abnormal axon extension, abnormal behavioral response to xenobiotic, abnormal cerebellar molecular layer, abnormal cerebral cortex morphology, abnormal cerebral cortex pyramidal cell morphology, abnormal dentate gyrus morphology, abnormal excitatory postsynaptic potential, abnormal forebrain development, abnormal hippocampus granule cell morphology, abnormal hippocampus layer morphology, [+]