tlr5 Phenotypes

Phenotypes

XB-GENEPAGE-480678

Gene Symbol: tlr5 Gene Name: toll like receptor 5

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tlr5 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal adipose tissue physiology, abnormal colon morphology, abnormal dendritic cell physiology, abnormal gut flora balance, abnormal leukocyte migration, abnormal macrophage physiology, abnormal physiological response to xenobiotic, abnormal response to transplant, decreased colon length, decreased interleukin-12b secretion, decreased interleukin-6 secretion, decreased susceptibility to bacterial infection, decreased total fat pad weight, immune system phenotype, increased epididymal fat pad weight, increased fasting circulating glucose level, increased interleukin-1 beta secretion, increased susceptibility to autoimmune diabetes, increased susceptibility to colitis induced morbidity/mortality, increased susceptibility to diet-induced obesity, increased susceptibility to induced colitis, increased susceptibility to induced pancreatitis, increased systemic arterial blood pressure, increased systemic arterial diastolic blood pressure, increased systemic arterial systolic blood pressure, increased total body fat amount, increased total fat pad weight [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal adipose tissue physiology, abnormal colon morphology, abnormal dendritic cell physiology, abnormal gut flora balance, abnormal leukocyte migration, abnormal macrophage physiology, abnormal physiological response to xenobiotic, abnormal response to transplant, decreased colon length, decreased interleukin-12b secretion, [+]