| Monarch Ortholog Phenotypes
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Human (9 sources):
Congenital corneal dystrophy,
Corneal dystrophy,
Corneal guttata,
Corneal opacity,
Nystagmus,
Opacification of the corneal stroma,
Reduced visual acuity,
Sensorineural hearing impairment,
Visual impairment
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Mouse (12 sources):
abnormal corneal stroma morphology,
abnormal spiral ligament fibrocyte morphology,
abnormal vestibular labyrinth morphology,
decreased endocochlear potential,
decreased urine creatine level,
decreased urine osmolality,
decreased urine sodium level,
increased Descemet membrane thickness,
increased corneal epithelium thickness,
increased corneal stroma thickness,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.