| Monarch Ortholog Phenotypes
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Human (27 sources):
Abnormal facial shape,
Abnormal venous morphology,
Angiosarcoma,
Ankle swelling,
Behavioral abnormality,
Capillary hemangioma,
Cellulitis,
Epicanthus,
Erysipelas,
Hemangioma,
Hydrocele testis,
Hyperkeratosis,
Hyperkeratosis over edematous areas,
Hypoplasia of lymphatic vessels,
Lichenification,
Lymphedema,
Neoplasm of the skin,
Nonimmune hydrops fetalis,
Papilloma,
Pedal edema,
Predominantly lower limb lymphedema,
Prominent superficial veins,
Specific learning disability,
Toenail dysplasia,
Upslanting toenail,
Urethral stricture,
Varicose veins
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Mouse (20 sources):
abnormal adipose tissue distribution,
abnormal anterior cardinal vein morphology,
abnormal dorsal aorta morphology,
abnormal lymph circulation,
abnormal lymphangiogenesis,
abnormal perineural vascular plexus morphology,
abnormal vascular development,
abnormal vitelline vascular remodeling,
cardiovascular system phenotype,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
extremity edema,
neonatal lethality, complete penetrance,
no abnormal phenotype detected,
pale yolk sac,
pericardial edema,
postnatal lethality,
prenatal lethality, complete penetrance,
reproductive system phenotype,
thick dermal layer
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.