nfe2 Phenotypes

Phenotypes

XB-GENEPAGE-483913

Gene Symbol: nfe2 Gene Name: nuclear factor, erythroid 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nfe2 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal hematopoietic system physiology, abnormal megakaryocyte morphology, absent platelets, decreased body size, decreased hemoglobin content, decreased survivor rate, enhanced megakaryocyte emperipolesis, increased acute myeloid leukemia incidence, increased bone ossification, increased compact bone mass, increased incidence of induced tumors, increased myeloid sarcoma incidence, increased osteoblast cell number, increased osteoclast cell number, increased sensitivity to induced morbidity/mortality, increased susceptibility to Retroviridae infection, increased trabecular bone volume, microcytosis, neonatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal hematopoietic system physiology, abnormal megakaryocyte morphology, absent platelets, decreased body size, decreased hemoglobin content, decreased survivor rate, enhanced megakaryocyte emperipolesis, increased acute myeloid leukemia incidence, increased bone ossification, increased compact bone mass, [+]