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XB-GENEPAGE-487698
htra1 HtrA serine peptidase 1
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal cartilage tissue (2 sources), abnormal ceratobranchial I morphology (2 sources), decreased size of the Meckel's cartilage (2 sources), decreased size of the ceratohyal (2 sources), decreased size of the head (2 sources), abnormal cell migration in neural crest (1 source), abnormal ethmoid region (1 source), absent dorsal fin (1 source), absent pigment cell (1 source), absent tail fin (1 source), decreased size of the head region (1 source), decreased size of the main body axis (1 source), decreased size of the palatoquadrate (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: htra1 manipulated (2 sources) |
| Computed annotations: htra1 assayed (7 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + htra1 (5 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (28 sources): Abnormality of extrapyramidal motor function, Arteriosclerosis of small cerebral arteries, Ataxia, Babinski sign, Dementia, Diffuse demyelination of the cerebral white matter, Diffuse white matter abnormalities, Dilation of Virchow-Robin spaces, Dysarthria, Gait disturbance, [+] |
| Mouse (4 sources): growth/size/body region phenotype, increased bone volume, increased trabecular bone thickness, vision/eye phenotype |
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View all ortholog results at Monarch |