abnormal involuntary movement, abnormal motor capabilities/coordination/movement, abnormal placenta morphology, abnormal placenta vasculature, abnormal secondary palate development, abnormal trophoblast layer morphology, abnormal tumor necrosis factor level, abnormal vitelline vasculature morphology, axonal dystrophy, cardiovascular system phenotype, cerebellum hemorrhage, convulsive seizures, crypts of Lieberkuhn abscesses, decreased placental labyrinth size, decreased regulatory T cell number, digestive/alimentary phenotype, embryonic growth retardation, embryonic lethality during organogenesis, incomplete penetrance, enlarged Peyer's patches, enlarged mesenteric lymph nodes, impaired limb coordination, impaired macrophage phagocytosis, increased autoantibody level, increased regulatory T cell number, increased susceptibility to bacterial infection induced morbidity/mortality, intestinal hemorrhage, intestinal ulcer, muscle hypertonia, muscle phenotype, neonatal lethality, complete penetrance, nervous system phenotype, palatal shelves fail to meet at midline, pericardial edema, premature death, small pharyngeal arch, spinal hemorrhage, thin myocardium, trabecula carnea hypoplasia