| Monarch Ortholog Phenotypes
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Human (11 sources):
Agalactia,
Amenorrhea,
Female hypogonadism,
Fibroadenoma of the breast,
Galactorrhea,
Hemorrhagic ovarian cyst,
Infertility,
Menorrhagia,
Oligomenorrhea,
Osteopenia,
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Mouse (43 sources):
abnormal Harderian gland morphology,
abnormal Harderian gland porphyrin secretion,
abnormal bone mineralization,
abnormal circulating calcium level,
abnormal decidualization,
abnormal hair cycle,
abnormal lactation,
abnormal mammary gland development,
abnormal maternal behavior,
abnormal maternal nurturing,
abnormal neuron proliferation,
abnormal oogenesis,
abnormal oviduct environment,
abnormal ovulation,
abnormal pancreatic islet morphology,
abnormal prostate gland epithelium morphology,
abnormal prostate gland ventral lobe morphology,
abnormal pup retrieval,
abnormal sexual interaction,
abnormal uterine environment,
behavior/neurological phenotype,
decreased abdominal fat pad weight,
decreased bone mass,
decreased circulating estradiol level,
decreased circulating progesterone level,
decreased insulin secretion,
decreased pancreatic beta cell mass,
decreased primary ovarian follicle number,
decreased thyroxine level,
delayed bone ossification,
endocrine/exocrine gland phenotype,
homeostasis/metabolism phenotype,
increased circulating parathyroid hormone level,
increased circulating prolactin level,
increased prostate gland weight,
increased seminal vesicle weight,
increased thyroid carcinoma incidence,
reduced male fertility,
reproductive system phenotype,
slow postnatal weight gain,
small pancreatic islets,
taste/olfaction phenotype,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.