| Monarch Ortholog Phenotypes
|
Human (36 sources):
Anxiety,
Attention deficit hyperactivity disorder,
Autistic behavior,
Blepharophimosis,
Broad nasal tip,
Compulsive behaviors,
Constipation,
Craniosynostosis,
Delayed speech and language development,
Diarrhea,
Epicanthus,
Feeding difficulties,
Generalized hypotonia,
Global developmental delay,
High palate,
Hypertrichosis,
Intellectual disability,
Joint hypermobility,
Kyphosis,
Long face,
Microcephaly,
Motor delay,
Narrow mouth,
Otitis media,
Pes planus,
Posteriorly rotated ears,
Prominent nasal bridge,
Ptosis,
Scoliosis,
Seizure,
Short stature,
Strabismus,
Tall chin,
Telecanthus,
Upslanted palpebral fissure,
obsolete Toe walking
[+]
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Mouse (11 sources):
abnormal placenta labyrinth morphology,
abnormal placenta vasculature,
abnormal syncytiotrophoblast morphology,
abnormal trophoblast layer morphology,
decreased embryo size,
decreased spongiotrophoblast cell number,
decreased trophoblast giant cell number,
disorganized placental labyrinth,
lethality throughout fetal growth and development, complete penetrance,
no abnormal phenotype detected,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.