rnf168 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (149)

Interactants (21)

XB-GENEPAGE-5765248

Gene Symbol: rnf168 Gene Name: ring finger protein 168, E3 ubiquitin protein ligase

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (46 sources): Abdominal pain, Abnormal cerebral white matter morphology, Abnormal facial shape, Abnormal pulmonary interstitial morphology, Arthritis, Ataxia, Bronchitis, Chromosomal breakage induced by ionizing radiation, Chronic sinusitis, Clumsiness, Conjunctival telangiectasia, Decreased circulating IgA level, Decreased circulating IgG level, Decreased circulating total IgM, Demyelinating peripheral neuropathy, Diarrhea, Dry skin, Elevated alpha-fetoprotein, Emotional lability, Enuresis nocturna, Erythema, Gait disturbance, Generalized lymphadenopathy, Global developmental delay, Headache, Immunodeficiency, Increased sensitivity to ionizing radiation, Intraventricular hemorrhage, Microcephaly, Mild global developmental delay, Neonatal asphyxia, Otitis media, Pneumonia, Poor hand-eye coordination, Pulmonary fibrosis, Recurrent fever, Recurrent pneumonia, Recurrent sinusitis, Recurrent viral infections, Respiratory insufficiency, Restrictive ventilatory defect, Scaling skin, Short stature, Specific learning disability, Telangiectasia, Weight loss [+]
Mouse (19 sources): abnormal T cell receptor delta chain V(D)J recombination, abnormal cell cycle checkpoint function, abnormal class switch recombination, abnormal snout morphology, chromosomal instability, decreased IgG1 level, decreased IgG2a level, decreased IgG3 level, decreased gamma-delta T cell number, decreased litter size, decreased male germ cell number, eyelids fail to open, immune system phenotype, increased DN3 thymocyte number, increased cellular sensitivity to ionizing radiation, increased cellular sensitivity to ultraviolet irradiation, increased double-negative T cell number, increased grip strength, reduced male fertility [+]
View all ortholog results at Monarch