| Monarch Ortholog Phenotypes
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Human (29 sources):
Abnormal electroretinogram,
Abnormality of the kidney,
Cognitive impairment,
Cryptorchidism,
Downslanted palpebral fissures,
Finger syndactyly,
Generalized hirsutism,
Hearing impairment,
Hepatic fibrosis,
Hypertension,
Hypogonadism,
Hypoplasia of penis,
Hypoplasia of the ovary,
Intellectual disability,
Low-set, posteriorly rotated ears,
Medial flaring of the eyebrow,
Multicystic kidney dysplasia,
Nephrotic syndrome,
Neurological speech impairment,
Nystagmus,
Obesity,
Pigmentary retinopathy,
Polydactyly,
Postaxial hand polydactyly,
Prominent nasal bridge,
Rod-cone dystrophy,
Short neck,
Short stature,
Skeletal muscle atrophy
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Mouse (15 sources):
abnormal bone marrow morphology,
abnormal fat cell morphology,
decreased birth body size,
decreased circulating free fatty acids level,
decreased circulating interleukin-6 level,
decreased circulating tumor necrosis factor level,
increased adipocyte glucose uptake,
increased circulating adiponectin level,
increased circulating glucose level,
increased epididymal fat pad weight,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.