| Monarch Ortholog Phenotypes
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Human (8 sources):
Dislocated radial head,
Global developmental delay,
Hypertelorism,
Prominent forehead,
Scoliosis,
Sensorineural hearing impairment,
Short stature,
Wide nasal bridge
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Mouse (22 sources):
abnormal chondrocyte morphology,
abnormal chondrocyte physiology,
abnormal contextual conditioning behavior,
abnormal craniofacial morphology,
abnormal epiphyseal plate morphology,
abnormal liver size,
abnormal long bone epiphyseal plate proliferative zone,
abnormal placenta morphology,
abnormal placenta vasculature,
abnormal pulmonary alveolar sac morphology,
abnormal thoracic cage shape,
chondrodystrophy,
decreased body size,
decreased fetal size,
domed cranium,
impaired contextual conditioning behavior,
increased heart weight,
neonatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
reproductive system phenotype,
respiratory system phenotype,
sternebra fusion
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.