sh2d1a Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (50)

Interactants (24)

XB-GENEPAGE-6076867

Gene Symbol: sh2d1a Gene Name: SH2 domain containing 1A

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources): Anemia, Decreased circulating IgG level, Fulminant hepatitis, Hepatic encephalopathy, Hepatomegaly, Immunodeficiency, Increased circulating IgM level, Infectious encephalitis, Lymphadenopathy, Lymphocytosis, Lymphoma, Meningitis, Pancytopenia, Recurrent pharyngitis, Reduced natural killer cell activity, Splenomegaly, Thrombocytopenia [+]
Mouse (33 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal NK T cell morphology, abnormal NK T cell physiology, abnormal T-helper 1 cell morphology, abnormal T-helper 2 cell morphology, abnormal cytotoxic T cell physiology, abnormal germinal center B cell morphology, abnormal germinal center B cell physiology, abnormal humoral immune response, abnormal long lived plasma cell morphology, abnormal memory T cell physiology, absent NK T cells, chronic inflammation, decreased CD4-positive, alpha beta T cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG3 level, decreased NK T cell number, decreased germinal center B cell number, decreased interferon-gamma secretion, decreased interleukin-21 secretion, decreased spleen germinal center number, decreased susceptibility to parasitic infection, decreased transitional stage B cell number, immune system phenotype, impaired natural killer cell mediated cytotoxicity, increased CD8-positive, alpha-beta T cell number, increased IgG2a level, increased T cell proliferation, increased natural killer cell mediated cytotoxicity, increased susceptibility to Riboviria infection, increased susceptibility to parasitic infection [+]
View all ortholog results at Monarch