Cerebral hemorrhage, Chest pain, Cholestasis, Choroid plexus cyst, Conductive hearing impairment, Congestive heart failure, Cranial nerve compression, Cutaneous leiomyoma, Cutaneous leiomyosarcoma, Decreased fumarate hydratase activity, Depressed nasal bridge, Dysphonia, Elevated calcitonin, Elevated urinary dopamine, Elevated urinary epinephrine, Elevated urinary norepinephrine, Episodic abdominal pain, Episodic hyperhidrosis, Episodic paroxysmal anxiety, Esophageal neoplasm, Extraadrenal pheochromocytoma, Failure to thrive, Fatigue, Flushing, Frontal bossing, Generalized hypotonia, Global developmental delay, Glomerular sclerosis, Hematuria, Hepatic failure, High palate, Hyperbilirubinemia, Hypercalcemia, Hypertelorism, Hypertension associated with pheochromocytoma, Hypertensive retinopathy, Hypoplasia of the brainstem, Hypotonia, Intellectual disability, profound, Lactic acidosis, Metabolic acidosis, Microcephaly, Multiple cutaneous leiomyomas, Nausea, Neurological speech impairment, Open operculum, Optic atrophy, Pallor, Palpitations, Panic attack, Papillary renal cell carcinoma type 2, Paraganglioma, Paraganglioma of head and neck, Paroxysmal vertigo, Polycythemia, Polymicrogyria, Positive regitine blocking test, Proteinuria, Pruritus, Pulsatile tinnitus, Recurrent paroxysmal headache, Reduced subcutaneous adipose tissue, Relative macrocephaly, Renal cell carcinoma, Retinal capillary hemangioma, Sinus tachycardia, Status epilepticus, Tremor, Uterine leiomyoma, Uterine leiomyosarcoma, Vaginal neoplasm, Visual impairment, Vocal cord paralysis, Weight loss