Monarch Ortholog Phenotypes
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Mouse (43 sources):
abnormal cell death,
abnormal colon morphology,
abnormal eye development,
abnormal gamma-delta T cell morphology,
abnormal hepatocyte morphology,
abnormal interleukin level,
abnormal intestinal epithelium morphology,
abnormal intestine regeneration,
abnormal limb morphology,
abnormal lymphocyte physiology,
abnormal myogenesis,
abnormal neuron physiology,
abnormal response/metabolism to endogenous compounds,
abnormal small intestine crypts of Lieberkuhn morphology,
abnormal tumor necrosis factor level,
decreased B cell proliferation,
decreased IgG1 level,
decreased T cell proliferation,
decreased body size,
decreased double-positive T cell number,
decreased interleukin-17 secretion,
decreased marginal zone B cell number,
decreased survivor rate,
distorted hair follicle pattern,
embryonic lethality, incomplete penetrance,
epidermal hyperplasia,
epidermal necrosis,
homeostasis/metabolism phenotype,
immune system phenotype,
increased hepatocyte apoptosis,
increased neuron apoptosis,
increased neutrophil cell number,
increased sensitivity to xenobiotic induced morbidity/mortality,
increased susceptibility to endotoxin shock,
increased susceptibility to induced colitis,
lethality throughout fetal growth and development, complete penetrance,
liver hypoplasia,
megacolon,
no abnormal phenotype detected,
premature death,
skin fibrosis,
slow postnatal weight gain,
small hair follicles
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