Monarch Ortholog Phenotypes
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Human (30 sources):
Acanthosis nigricans,
Accelerated skeletal maturation,
Ambiguous genitalia, female,
Bone pain,
Cryptorchidism,
Delayed epiphyseal ossification,
Delayed skeletal maturation,
Enlarged polycystic ovaries,
Eunuchoid habitus,
Female infertility,
Female pseudohermaphroditism,
Generalized hirsutism,
Genu valgum,
Growth delay,
Gynecomastia,
Hepatic steatosis,
Hypergonadotropic hypogonadism,
Hyperlipidemia,
Insulin resistance,
Macroorchidism, postpubertal,
Male infertility,
Maternal virilization in pregnancy,
Obesity,
Osteopenia,
Osteoporosis,
Ovarian cyst,
Primary amenorrhea,
Short stature,
Tall stature,
Type II diabetes mellitus
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Mouse (105 sources):
abnormal acrosome morphology,
abnormal adipose tissue amount,
abnormal baroreceptor physiology,
abnormal circulating alkaline phosphatase level,
abnormal circulating cholesterol level,
abnormal copulation,
abnormal enzyme/coenzyme level,
abnormal epididymis morphology,
abnormal exploration in a new environment,
abnormal labium morphology,
abnormal lean body mass,
abnormal lipid homeostasis,
abnormal liver lobule morphology,
abnormal locomotor activation,
abnormal male germ cell apoptosis,
abnormal mating frequency,
abnormal mature ovarian follicle morphology,
abnormal ovarian follicle morphology,
abnormal parental behavior,
abnormal primary sex determination,
abnormal prostate gland physiology,
abnormal seminiferous tubule epithelium morphology,
abnormal seminiferous tubule morphology,
abnormal sexual interaction,
abnormal short term spatial reference memory,
abnormal spermatid morphology,
abnormal spermiogenesis,
abnormal spleen germinal center morphology,
abnormal systemic arterial blood pressure,
abnormal uterus development,
abnormal white adipose tissue morphology,
absent corpus luteum,
absent ovarian follicles,
anovulation,
arrest of spermiogenesis,
asthenozoospermia,
decreased aggression,
decreased aggression towards male mice,
decreased bone mass,
decreased circulating alkaline phosphatase level,
decreased circulating estradiol level,
decreased exploration in new environment,
decreased heart rate variability,
decreased large unstained cell number,
decreased lean body mass,
decreased locomotor activity,
decreased male germ cell number,
decreased mean systemic arterial blood pressure,
decreased systemic arterial diastolic blood pressure,
decreased testis weight,
decreased uterus weight,
enlarged mesenteric lymph nodes,
enlarged prostate gland,
enlarged salivary gland,
failure of ejaculation,
homeostasis/metabolism phenotype,
impaired luteinization,
impaired ovarian folliculogenesis,
increased abdominal adipose tissue amount,
increased abdominal fat pad weight,
increased aggression towards female mice,
increased anti-single stranded DNA antibody level,
increased anxiety-related response,
increased autoantibody level,
increased bone marrow cell number,
increased cardiac muscle contractility,
increased circulating dihydrotestosterone level,
increased circulating estradiol level,
increased circulating glucose level,
increased circulating prolactin level,
increased dendritic cell number,
increased fasting circulating glucose level,
increased fibroadenoma incidence,
increased gonadal fat pad weight,
increased granulocyte number,
increased granulosa cell apoptosis,
increased grooming behavior,
increased incidence of tumors by chemical induction,
increased macrophage cell number,
increased mammary fat pad weight,
increased mammary gland tumor incidence,
increased mature B cell number,
increased osteoclast cell number,
increased ovary apoptosis,
increased prostate gland weight,
increased renal fat pad weight,
increased seminal vesicle weight,
increased susceptibility to autoimmune disorder,
increased susceptibility to weight gain,
increased total body fat amount,
lacrimal gland inflammation,
mammary gland duct hyperplasia,
mammary gland hyperplasia,
no abnormal phenotype detected,
ovary hemorrhage,
pale liver,
reduced male fertility,
reduced male mating frequency,
renal glomerular immunoglobulin deposits,
reproductive system phenotype,
salivary gland inflammation,
small uterus,
spleen hyperplasia,
thin endometrium,
thin myometrium
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View all ortholog results at Monarch
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