pfdn1 Phenotypes

Phenotypes

XB-GENEPAGE-955619

Gene Symbol: pfdn1 Gene Name: prefoldin subunit 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pfdn1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal B cell activation, abnormal T cell activation, abnormal brain commissure morphology, abnormal brain white matter morphology, abnormal embryo size, abnormal spleen red pulp morphology, abnormal spleen white pulp morphology, abnormal splenic cell ratio, abnormal tail morphology, abnormal thymus cell ratio, abnormal thymus morphology, decreased B-1 B cell number, decreased B-2 B cell number, decreased birth body size, decreased bone marrow cell number, decreased corpus callosum size, decreased erythrocyte cell number, decreased locomotor activity, decreased pre-B cell number, decreased thymus weight, premature death, preweaning lethality, complete penetrance, slow postnatal weight gain, small spleen [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal B cell activation, abnormal T cell activation, abnormal brain commissure morphology, abnormal brain white matter morphology, abnormal embryo size, abnormal spleen red pulp morphology, abnormal spleen white pulp morphology, abnormal splenic cell ratio, abnormal tail morphology, abnormal thymus cell ratio, [+]