bloc1s2 Phenotypes

Phenotypes

XB-GENEPAGE-967290

Gene Symbol: bloc1s2 Gene Name: biogenesis of lysosomal organelles complex-1, subunit 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: bloc1s2 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (29 sources): abnormal abdominal wall morphology, abnormal body length, abnormal cerebral cortex morphology, abnormal cortical intermediate zone morphology, abnormal craniofacial morphology, abnormal embryo size, abnormal hematopoietic stem cell morphology, abnormal limb bud morphology, abnormal lysosome morphology, abnormal pericardium morphology, abnormal stratification in cerebral cortex, abnormal vesicle-mediated transport, absent eye pigmentation, decreased brain size, decreased circulating free fatty acids level, decreased granulocyte monocyte progenitor cell number, enlarged lateral ventricles, impaired hematopoiesis, impaired neuron differentiation, increased hematopoietic stem cell number, increased hematopoietic stem cell proliferation, increased neuronal precursor proliferation, increased radial glial cell number, loss of cortex neurons, neonatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, thin cerebral cortex, thin cortical plate [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (29 sources): abnormal abdominal wall morphology, abnormal body length, abnormal cerebral cortex morphology, abnormal cortical intermediate zone morphology, abnormal craniofacial morphology, abnormal embryo size, abnormal hematopoietic stem cell morphology, abnormal limb bud morphology, abnormal lysosome morphology, abnormal pericardium morphology, [+]