spint1 Phenotypes

Phenotypes

XB-GENEPAGE-968961

Gene Symbol: spint1 Gene Name: serine peptidase inhibitor, Kunitz type 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: spint1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (28 sources): abnormal basement membrane morphology, abnormal chorionic plate morphology, abnormal defecation, abnormal enterocyte proliferation, abnormal intestine physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal placenta development, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placenta vasculature, abnormal placental labyrinth vasculature morphology, abnormal placental transport, abnormal trophoblast giant cell morphology, abnormal trophoblast layer morphology, absent placental labyrinth, embryo phenotype, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, enlarged pericardium, increased embryonic tissue cell apoptosis, increased enterocyte apoptosis, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to induced colitis, increased susceptibility to weight loss, intestinal ulcer, preweaning lethality, complete penetrance, small cecum [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (28 sources): abnormal basement membrane morphology, abnormal chorionic plate morphology, abnormal defecation, abnormal enterocyte proliferation, abnormal intestine physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal placenta development, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placenta vasculature, [+]