| Monarch Ortholog Phenotypes
|
Human (40 sources):
Abnormal pinna morphology,
Abnormality of the skin,
Ataxia,
Brachycephaly,
Carpal bone hypoplasia,
Cerebral atrophy,
Coarse facial features,
Epicanthus,
Flared metaphysis,
Flat acetabular roof,
Generalized hypotonia,
Hirsutism,
Hypoplasia of the corpus callosum,
Hypotonia,
Intellectual disability,
Intellectual disability, severe,
Irregular epiphyses,
Irregular vertebral endplates,
Long fibula,
Low anterior hairline,
Low posterior hairline,
Metaphyseal irregularity,
Microcephaly,
Narrow iliac wing,
Nystagmus,
Platyspondyly,
Posterior scalloping of vertebral bodies,
Prominent forehead,
Seizure,
Short femoral neck,
Short neck,
Small basal ganglia,
Small epiphyses,
Spondyloepimetaphyseal dysplasia,
Strabismus,
Synophrys,
Thick lower lip vermilion,
Ventriculomegaly,
Wide nose,
obsolete Joint laxity
[+]
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|
Mouse (7 sources):
abnormal embryo size,
decreased heart weight,
decreased lean body mass,
embryonic lethality prior to tooth bud stage,
increased total body fat amount,
prenatal lethality prior to heart atrial septation,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.