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Summary Expression Phenotypes Gene Literature (22) GO Terms (4) Nucleotides (66) Proteins (30) Interactants (151) Wiki
XB-GENEPAGE-979946

dio1     deiodinase, iodothyronine type 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dio1 assayed (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (2 sources): Euthyroid hyperthyroxinemia, Goiter
Mouse (6 sources): abnormal feces composition, abnormal kidney morphology, abnormal response/metabolism to endogenous compounds, abnormal thyroid hormone level, increased thyroxine level, increased triiodothyronine level

View all ortholog results at Monarch