atp6v0c Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-981789

Gene Symbol: atp6v0c Gene Name: ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal eye morphology (10 sources), abnormal branchial arch skeleton morphology (8 sources), decreased size of the branchial arch skeleton (7 sources), abnormal Meckel's cartilage morphology (5 sources), abnormal brain morphology (5 sources), abnormal inner ear morphology (5 sources), absent inner ear (5 sources), fused eyes (5 sources), decreased size of the Meckel's cartilage (4 sources), abnormal olfactory pit morphology (3 sources), decreased size of the pharyngeal arch (3 sources), increased pigmentation in the optic nerve (3 sources), increased pigmentation in the optic stalk (3 sources), abnormal optic vesicle morphology (2 sources), abnormal pre-chordal neural plate morphology (2 sources), absent olfactory pit (2 sources), decreased size of the eye (2 sources), duplicated eye (2 sources), increased thickness of the optic stalk (2 sources), abnormal anatomical region morphology (1 source), abnormal cartilage element morphology (1 source), abnormal establishment of tissue polarity (1 source), abnormal head morphology (1 source), abnormal lens morphology (1 source), abnormal optic nerve morphology (1 source), abnormal periocular region morphology (1 source), abnormal pharyngeal arch morphology (1 source), abnormal tooth morphology (1 source), abnormally increased volume of brain (1 source), abnormally localised eye (1 source), abnormally localised inner ear (1 source), absent Meckel's cartilage (1 source), absent eye (1 source), absent optic stalk (1 source), decreased width of the pre-chordal neural plate (1 source), duplicated head (1 source), duplicated lens (1 source), fused optic stalks (1 source), increased pigmentation in the head (1 source), increased size of the cell in cranial neural crest (1 source), increased size of the cranial neural crest (1 source), increased size of the eye (1 source), increased thickness of the optic nerve (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal eye morphology (10 sources), abnormal branchial arch skeleton morphology (8 sources), decreased size of the branchial arch skeleton (7 sources), abnormal Meckel's cartilage morphology (5 sources), abnormal brain morphology (5 sources), abnormal inner ear morphology (5 sources), absent inner ear (5 sources), fused eyes (5 sources), decreased size of the Meckel's cartilage (4 sources), abnormal olfactory pit morphology (3 sources), decreased size of the pharyngeal arch (3 sources), increased pigmentation in the optic nerve (3 sources), increased pigmentation in the optic stalk (3 sources), abnormal optic vesicle morphology (2 sources), abnormal pre-chordal neural plate morphology (2 sources), absent olfactory pit (2 sources), decreased size of the eye (2 sources), duplicated eye (2 sources), increased thickness of the optic stalk (2 sources), abnormal anatomical region morphology (1 source), abnormal cartilage element morphology (1 source), abnormal establishment of tissue polarity (1 source), abnormal head morphology (1 source), abnormal lens morphology (1 source), abnormal optic nerve morphology (1 source), abnormal periocular region morphology (1 source), abnormal pharyngeal arch morphology (1 source), abnormal tooth morphology (1 source), abnormally increased volume of brain (1 source), abnormally localised eye (1 source), abnormally localised inner ear (1 source), absent Meckel's cartilage (1 source), absent eye (1 source), absent optic stalk (1 source), decreased width of the pre-chordal neural plate (1 source), duplicated head (1 source), duplicated lens (1 source), fused optic stalks (1 source), increased pigmentation in the head (1 source), increased size of the cell in cranial neural crest (1 source), increased size of the cranial neural crest (1 source), increased size of the eye (1 source), increased thickness of the optic nerve (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: atp6v0c manipulated (9 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + atp6v0cdel (33 sources), Xla Wt + atp6v0c (9 sources), Xla Wt + atp6v0cdel (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (4 sources): abnormal embryonic tissue morphology, abnormal inner cell mass morphology, embryonic lethality before implantation, complete penetrance, failure of zygotic cell division