Monarch Ortholog Phenotypes
|
Human (31 sources):
Abnormal electroretinogram,
Abnormal retinal vascular morphology,
Abnormal testis morphology,
Abnormality of fundus pigmentation,
Abnormality of retinal pigmentation,
Anteverted nares,
Atypical scarring of skin,
Blindness,
Cataract,
Conductive hearing impairment,
Constriction of peripheral visual field,
Glaucoma,
Hyperinsulinemia,
Hyperreflexia,
Hypogonadism,
Hypoplasia of penis,
Intellectual disability,
Keratoconus,
Moderate albuminuria,
Nyctalopia,
Nystagmus,
Obesity,
Ophthalmoplegia,
Optic atrophy,
Photophobia,
Progressive night blindness,
Rod-cone dystrophy,
Sensorineural hearing impairment,
Type II diabetes mellitus,
Visual impairment,
Wide nasal bridge
[+]
|
Mouse (103 sources):
abnormal Langerhans cell morphology,
abnormal Langerhans cell physiology,
abnormal atrial thrombosis,
abnormal auchene hair morphology,
abnormal branching of the mammary ductal tree,
abnormal cauda epididymis morphology,
abnormal chemokine level,
abnormal colon morphology,
abnormal coronary artery morphology,
abnormal cytokine level,
abnormal glial cell morphology,
abnormal hair follicle morphology,
abnormal hepatocyte morphology,
abnormal horizontal vestibuloocular reflex,
abnormal interleukin level,
abnormal keratinocyte physiology,
abnormal kidney blood vessel morphology,
abnormal liver sinusoid morphology,
abnormal macrophage physiology,
abnormal male germ cell apoptosis,
abnormal optokinetic reflex,
abnormal ovarian folliculogenesis,
abnormal ovulation,
abnormal primordial ovarian follicle morphology,
abnormal rod electrophysiology,
abnormal seminiferous tubule epithelium morphology,
abnormal skin condition,
abnormal sperm head morphology,
abnormal spermiation,
abnormal spleen red pulp morphology,
abnormal stomach pyloric region morphology,
abnormal superovulation,
abnormal thrombosis,
abnormal tumor necrosis factor level,
abnormal urinary bladder blood vessel morphology,
abnormal urinary bladder urothelium morphology,
abnormal uterus morphology,
abnormal xenobiotic pharmacokinetics,
acanthosis,
cardiac fibrosis,
cardiovascular system phenotype,
coiled sperm flagellum,
cystolithiasis,
decreased corpora lutea number,
decreased epididymis weight,
decreased fertilization frequency,
decreased germ cell number,
decreased litter size,
decreased liver weight,
decreased ovary weight,
decreased physiological sensitivity to xenobiotic,
decreased seminal vesicle weight,
decreased sensitivity to xenobiotic induced morbidity/mortality,
decreased spleen germinal center size,
decreased spleen white pulp amount,
decreased susceptibility to ischemic brain injury,
decreased susceptibility to type IV hypersensitivity reaction,
decreased testis weight,
dilated piliary canal,
disorganized retina layers,
folliculitis,
gastric polyps,
heart inflammation,
homeostasis/metabolism phenotype,
hypergranulosis,
increased heart weight,
increased hepatoma incidence,
increased incidence of tumors by chemical induction,
increased liver adenoma incidence,
increased neuronal precursor cell number,
increased physiological sensitivity to xenobiotic,
increased retina apoptosis,
increased sensitivity to xenobiotic induced morbidity/mortality,
increased spleen weight,
increased susceptibility to injury,
increased urinary bladder carcinoma incidence,
liver hyperplasia,
microvesicular hepatic steatosis,
multinucleated giant male germ cells,
nervous system phenotype,
pale liver,
patent ductus venosus,
photoreceptor outer segment degeneration,
postnatal lethality, incomplete penetrance,
premature death,
pulmonary alveolar edema,
reduced female fertility,
renal/urinary system phenotype,
reproductive system phenotype,
retina outer nuclear layer degeneration,
retina photoreceptor degeneration,
seminiferous tubule degeneration,
short photoreceptor outer segment,
skeleton phenotype,
skin lesions,
small liver,
small ovary,
small prostate gland anterior lobe,
small prostate gland dorsolateral lobe,
small spleen,
thick skin,
urinary bladder fibrosis,
vascular smooth muscle hypertrophy
[+]
|
View all ortholog results at Monarch
|