cldn18 Phenotypes

Phenotypes

XB-GENEPAGE-991170

Gene Symbol: cldn18 Gene Name: claudin 18

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cldn18 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (23 sources): abnormal gastric chief cell morphology, abnormal gastric parietal cell morphology, abnormal lung weight, abnormal osteoclast differentiation, abnormal pulmonary alveolar system morphology, abnormal pulmonary alveolus epithelium morphology, abnormal seminal vesicle morphology, decreased blood urea nitrogen level, decreased bone mass, decreased bone mineral content, decreased bone strength, decreased bone trabecula number, decreased trabecular bone connectivity density, decreased trabecular bone thickness, decreased trabecular bone volume, enlarged lung, homeostasis/metabolism phenotype, impaired lung alveolus development, increased lung weight, increased osteoclast cell number, increased type II pneumocyte number, skeleton phenotype, small superior vagus ganglion [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (23 sources): abnormal gastric chief cell morphology, abnormal gastric parietal cell morphology, abnormal lung weight, abnormal osteoclast differentiation, abnormal pulmonary alveolar system morphology, abnormal pulmonary alveolus epithelium morphology, abnormal seminal vesicle morphology, decreased blood urea nitrogen level, decreased bone mass, decreased bone mineral content, [+]