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Summary Expression Phenotypes Gene Literature (0) GO Terms (8) Nucleotides (78) Proteins (31) Interactants (7) Wiki
XB-GENEPAGE-996038

plekhf1     pleckstrin homology and FYVE domain containing 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: plekhf1 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (7 sources): abnormal endocytosis, abnormal macrophage physiology, decreased circulating interferon-beta level, decreased circulating interleukin-6 level, decreased circulating tumor necrosis factor level, increased susceptibility to bacterial infection induced morbidity/mortality, preweaning lethality, complete penetrance