Glomus anatomy- pronephros

Glomus anatomy

The glomus (plural glomera) is the vascularized structure that filters wastes from the blood in embryos with simple embryonic pronephroi. Filtrate passes from the glomus to the coelom. The vascularized component of the kidney is referred to as a glomus (= ball) when its length extends for greater than one body segment. If it extends over one segment or less, it is referred to as a glomerulus. I would prefer to refer to integrated vascular structures as glomeruli, and external vascularized structures as glomera.

The glomus forms from a pocket of the splanchnic mesoderm which pushes into the coelom at about stage 29 in Xenopus (Nieuwkoop and Faber, 1994). This pocket is vascularized by a blood vessel from the dorsal aorta. The enlargements of the figures below are very nice, and worth the download time.
A. B.
A. Transverse section of stage 37 Xenopus (H&E) showing the right hand side glomus, coelom and pronephric tubules (histology by Dan Seufert).
B. Transverse section through the plane of the left glomus (glm) by Herbert Field (1891, plate 47).
Search PubMed for papers by Peter Vize or by Dan Seufert
or for other papers on glomeral development in frogs

References; Field, H.H. The development of the pronephros and segmental duct in amphibia. Bull.Mus.Comp.Zool. 21: 200-
Carroll, T.J. and Vize, P.D. (1996) The Wilms' tumor suppressor gene is involved in the development of disparate kidney forms: evidence from expression in the Xenopus pronephros. Developmental Dynamics, in press.
Nieuwkoop, P.D. and Faber, J. (1994). Normal Table of Xenopus laevis (Daudin). New York, Garland.
Goodrich, E.S. (1986 reprint) Studies on the structure and development of vertebrates. Univ. of Chicago Press.
Jaffee, O.C. (1952) The morphogenesis of the pronephros of the leopard frog (Rana pipiens) and studies on pronephric function. Ph.D. Thesis, Indianna University. Peter Vize

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