What's New at the Xenopus Molecular Marker Resource?

• gene expression patterns are finally migrating to Xenbase. The link to shh below is a good example. The new format will link in a ot of information when completed.
• shh, Apr 25, 2001
• Xenbase. Xenbase is the next generation frog web site with many new features. The XMMR will be maintained but all new expansion will occur at Xenbase. The marker images of the XMMR are in the process of being copied over and enhanced.
• better NCBI links are being constantly added, visit some markers and let us know if you would like more/different links... The NCBI icon takes you to the NCBI, the name link takes you to PubMed papers by that author, and the subject link will search for related papers for you.
• an enormous number of Xenopus laevis AND tropicalis libraries are now available. Visit the libraries page. Apr 20, 2000
• a new Genomics page has been initiated. Visit the EST database (includes Xenopus) and the frog microarray project. More links resources soon. Apr 20, 2000
• Antisense news from Janet Heasman. April 5, 2000
• new pronephric tubule specific marker- XSMP-30, submitted by Akira Sato and Ryuichi Nishinakamura, 01/20/00.
• lots of meetings are scheduled in 2000. Please visit the meetings list...
• XPax-2 and XPax-8, added August 17th.
• mini-search panels are being added to each page that will allow you to instantly search PubMed, the super medline interface, for additional papers on your gene/marker of interest. Not on all pages yet, but will be soon. Try out the search on the gremlin page..... Project initiated August 17th, 1999.
• a link on the Methods page will take you to Lance Davidson's fluorescent in situ page
• A developmental series of TUNEL stainings, illustrating programmed cell death patterns in developing embryos. Submitted by Jean Gautier 19 July, 1999.
• a quicktime movie illustrating the expression of xk81 within a rotating tadpole head has been submitted by Lance Davidson. 6 July 99.
• axin images submitted by Peter Klein, 22 June 99.
• Gremlin, DAN family member, expressed in the pronephric duct and neural crest. Binds and regulates BMPs. Added June 8.
• A new search engine has been added (see the opening Welcome page), as the old version had some updating problems. This version requires Java (sorry to those of you who do not have this capacity). If you do not have Java it will not be visible. The search will show some advertisments when the results are shown, the price we pay for a free, fast search service. This service provides me with a weekly summary of searched terms, and I will attempt to add as many of the requested items as is possible. June 1, 1999.
• A direct link to the babelfish translator has been added to the welcome page. Simply click on the "Translate this page" botton and select the language you would like it translated to, an amazing free service!
• Final report from the Xenopus representatives at the NIH meeting on non-mammalian model systems. Please read this report.
• there is a new "other sites" page that more conveniently makes popular journals links, other labs, grants, searches, and many others, easier to use. The old page is still in place if you would prefer to bookmark it. Added May 4, 1999.
• Figure illustrating the life cycle, and useful embryonic stages of Xenopus. A high resolution (0.8 MB LZW compression) tiff file, a high resolution (0.5 MB) jpg file (either one can be used to generate a high quality slide) and a low resolution (0.01 MB) jpg file (suitable for a web page) are provided on the Xenopus stages page.
• update on Xenopus tropicalis meeting, March 26
• anti-nuclear lamin, contributed by Mike Klymkowsky, added Feb 18 99
• plaktoglobin, cortex, contiributed by Mike Klymkowsky
• beta catenin, cortex, contiributed by Mike Klymkowsky
• XVent1 and XVent2, ventral and ventrolateral marginal zone. Added Jan 15, 1999.
• A mirror of the XMMR has been set up in France by Denis Pugnére at the CNRS/IGH. This project will hopefully be extended to a French language based version in the furure. Thanks Denis! 01/01/99
• A counter has been added to both the opening Welcome Page and to the White Pages. Although in general these web pages are kept as simple as possible, making them both fast to load and functional with both basic and advanced web browsers, following the use of the page more closely will allow us to plan for changes and upgrades more effectively.
• Link to the Grainger lab X.tropicalis page. Read about the potential of this extraordinary system.
• Xpat, germ plasm and primordial germ cells, added June 30.
• X-Delta-2, prospective somte boundries. Added June 11.
• Pax-3, dorsal and posterior neural tube, Added June 10.
• stunning new photos of HoxB9 (Xlhbox6) in the posterior nervous system from Francesca Mariani. Added April 6.
• amazing photo of transgenic frog GFP expression from Enrique Amaya, 31 March.
• XMyoD, added 29 Jan 1998
• XMyf-5, a great marker for the dorsolateral marginal zone. added 29 Jan, 1998.
• New! Listing of graduate programs in developmental biology- please submit links!
• Xnot, presumptive notochord and organizer marker.
• correction to Xnot RT-PCR primer sequence from Kris Hostetler
• ets-1/ets-2 images from Pierre Remy
• a web page on developmental tumors caused by mutant p53.
• more eFGF images from Harv Isaacs, added Spet. 17.
• HoxD1 from Peggy Kolm, added 10.8.97.
• more RT-PCR primers from Katsunori Nakata
• cement gland marker update and new photos from the Sive lab via Peggy Kolm. XA, XAG and XCG.
• maps and data on GFP and Blue FP expression plasmids from Mike Klymkowski, May 29.
• A very powerful search function has been added by John Cordell. 30.3.97. Searches show the text that was matched and give a link to the page, so you know if you want to jump to it before you waste time. The WebGlimpse program can also allow spelling errors and can be set to bring up only recently modified pages, so for example you could type in "neural" and select "modified in last 20 days" and bring up all the new neural markers. Many thanks to John for compiling the code to run on NeXTSTEP!
• anti-neural monoclonal 2G9, stains CNS and lateral line. added 17.3.97
• A "search" function on the White Pages allows you to jump to names beginning with a specific letter. 17.3.97
• a link to Enrique Amaya's transgenic trouble-shooting guide
• Xen1, monoclonal CNS marker. Added 12/3/97.
• Xl-fli, an ets family member, a very useful endothelial marker, from Pierre Remy. 28.2.97
• some new goosecoid images from Susie Zoltewitz.. Added Feb 24.
• HoxB9 (=Xlhbox6) from Susie Zoltewitz. Added Feb 24.
• frog jobs, some postdoc positions are available in Xenopus labs!
• Information on the upcoming SDB and International Congress of Developmental Biology in Utah this July.
• Fritz Aberger has submitted some corrections to the En2 and Xbra RT-PCR oligos
• Monoclonal HNK-1 from Todd Verrastro, added 23/12/96
• Links to Xenopus development movies on-line, added Dec. 20.
• Link to information on the upcoming CSH course on the Early Development of Xenopus
• new Xenopus stage figures in a more Macintosh friendly format
• Expression plasmids. A listing of useful plasmids for generating mRNA or expression constructs for microinjection. Controls plasmids including beta-galactosidase, prolactin and GFP are included. Under construction, 17/8/96.
• Mad, component of the BMP activated transduction pathway, expressed in tailbud cranial crest. From Jerry Thomsen, 4/6/96.
• The XMMR is now available on CD-ROM. If you know of a colleague who does not have access to the internet, but who has a CD-ROM drive, please let me know. I will distribute copies for free as long as the number of requests is moderate. The links to other databases, e.g. GenBank, Entrez, Medline etc., obviously will not work on the CD-ROM version.
• anatomy of the glomus, H&E section by Dan Seufert. 30/4/96
• more information on cDNA libraries from Michael King. 25/4/96
• Slug (Xslu), pre- and post-migratory crest marker (cranial and trunk). 15/4/96.
• Listing of Xenopus cDNA and genomic libraries. 1/4/96.
• Santa Cruz Summer Conference on Developmental Biology Announcement.
• links to on-line abstracts made to each page when possible. For example, if you were looking at the Tor70 page and clicked on the reference.....
• New information on high resolution video capture, from Robert Davis. 27/2/96.
• registration forms are now available for the 6th International Xenopus Conference.
• Xlim-1, added 15/2/96.

• Information on the 6th International Xenopus Conference

• some templates for making your own html forms to submit to the XMMR are now available.
• XTin1, another heart homeobox gene (also known as XNKX-2.3), from Ondine Cleaver and Kris Patterson. Added 26/1/96.
• XNKX-2.5, a heart specific homeobox gene, from Kris Patterson. Added 26/1/96.
• a small icon at the top of each page will now link you back to the XMMR homepage
• int-2 (fgf-3), from Harry Isaacs. 18/1/96
• Xenopus elav-type ribonucleoprotein, Xl etr-1, pictures from Anne Knecht and Richard Harland, text from Peter Good and Anne Knecht. 3/1/96
• Xenopus choroid plexus lipocalin I, Xl cpl-1, pictures from Anne Knecht and Richard Harland, text from Peter Good and Anne Knecht. 3/1/96
• Xenopus synaptobrevin II, Xl sybII, nucleic acid. Pictures from Anne Knecht and Richard Harland, text from Peter Good and Anne Knecht. 3/1/96
• tubulin (yes, tubulin!) antibody, added 22/12/95.
• N-myc, both in situ hybridization and polyclonal antisera. 20/12/95
• Xenopus neural ribonucleoprotein, pictures from Anne Knecht, Richard Harland and Klaus Richter, text from Peter Good and Anne Knecht.
• new US Xenopus supplier, will also supply X.tropicalis in near future Xenopus Express also have a very useful web page.
• new Tor70 data and photo from Richard Harland and Francesca Mariani, added 3/10/95.
• xAG1, cement gland marker, 29/9/95.
• eFGF from Harry Isaacs, 20/9/95.
• PCR primer list for RT-PCR analysis, from Guenter Lepperdinger, 8/9/95.
• benzidene stain for red blood cells from Jerry Thomsen. added 5/9/95.
• nodal related xnr3 from Richard Harland and Bill Smith, added 31/8/95.
• CyclinD1 from Matt Cockerill, added 23/8/95.
• Xwnt8, Xwnt4, and Xwnt otic staining from Randy Moon and Jan Christian, added 22/8/95
• Chordin, added 11/8/95.
• BMP2 and BMP4 from Ali Hemmati-Brivanlou and Jerry Thomsen, added 11/8/95.

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