Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (1) GO Terms (7) Nucleotides (266) Proteins (35) Interactants (113) Wiki
XB-GENEPAGE-941687
???displayGene.symbol???:
 mgmt

???displayGene.name???: 
O-6-methylguanine-DNA methyltransferase

???displayGene.synonyms???
LOC108697181 ( Nomenclature history )

???displayGene.geneFunction???
6-O-methylguanine-DNA methyltransferase MGMT/MGT1, involved in DNA repair

Protein Function :
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transfe...[+]


InterPro :
MethylG MeTrfase N, MGMT N sf, MethylDNA cys MeTrfase AS, WH-like DNA-bd sf, [+]

???displayGene.geneInteractants???
Human Physical (0), Co-citation (113)

Diseases: 


External Links:
 
Gene ID & Location
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info