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Summary Expression Phenotypes Gene Literature (93) GO Terms (6) Nucleotides (169) Proteins (117) Interactants (131) Wiki
XB-GENEPAGE-922335

Papers associated with kcnma1



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Calcium-activated potassium channels expressed from cloned complementary DNAs., Adelman JP, Shen KZ, Kavanaugh MP, Warren RA, Wu YN, Lagrutta A, Bond CT, North RA., Neuron. August 1, 1992; 9 (2): 209-16.

Reconstitution of expressed KCa channels from Xenopus oocytes to lipid bilayers., Pérez G, Lagrutta A, Adelman JP, Toro L., Biophys J. April 1, 1994; 66 (4): 1022-7.

Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004., McKay MC, Dworetzky SI, Meanwell NA, Olesen SP, Reinhart PH, Levitan IB, Adelman JP, Gribkoff VK., J Neurophysiol. May 1, 1994; 71 (5): 1873-82.

Cloned Ca(2+)-dependent K+ channel modulated by a functionally associated protein kinase., Esguerra M, Wang J, Foster CD, Adelman JP, North RA, Levitan IB., Nature. June 16, 1994; 369 (6481): 563-5.

A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels., Meera P, Wallner M, Jiang Z, Toro L., FEBS Lett. March 11, 1996; 382 (1-2): 84-8.

A cysteine-rich domain defined by a novel exon in a slo variant in rat adrenal chromaffin cells and PC12 cells., Saito M, Nelson C, Salkoff L, Lingle CJ., J Biol Chem. May 2, 1997; 272 (18): 11710-7.

Voltage-controlled gating in a large conductance Ca2+-sensitive K+channel (hslo)., Stefani E, Ottolia M, Noceti F, Olcese R, Wallner M, Latorre R, Toro L., Proc Natl Acad Sci U S A. May 13, 1997; 94 (10): 5427-31.

dSLo interacting protein 1, a novel protein that interacts with large-conductance calcium-activated potassium channels., Xia Xm, Hirschberg B, Smolik S, Forte M, Adelman JP., J Neurosci. April 1, 1998; 18 (7): 2360-9.

Control of alternative splicing of potassium channels by stress hormones., Xie J, McCobb DP., Science. April 17, 1998; 280 (5362): 443-6.

Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel., Díaz L, Meera P, Amigo J, Stefani E, Alvarez O, Toro L, Latorre R., J Biol Chem. December 4, 1998; 273 (49): 32430-6.

Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog., Wallner M, Meera P, Toro L., Proc Natl Acad Sci U S A. March 30, 1999; 96 (7): 4137-42.

Transplantable sites confer calcium sensitivity to BK channels., Schreiber M, Yuan A, Salkoff L., Nat Neurosci. May 1, 1999; 2 (5): 416-21.

Molecular basis for the inactivation of Ca2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells., Xia XM, Ding JP, Lingle CJ., J Neurosci. July 1, 1999; 19 (13): 5255-64.

MEK and Cdc2 kinase are sequentially required for Golgi disassembly in MDCK cells by the mitotic Xenopus extracts., Kano F, Takenaka K, Yamamoto A, Nagayama K, Nishida E, Murata M., J Cell Biol. April 17, 2000; 149 (2): 357-68.                      

A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin., Meera P, Wallner M, Toro L., Proc Natl Acad Sci U S A. May 9, 2000; 97 (10): 5562-7.

Rectification and rapid activation at low Ca2+ of Ca2+-activated, voltage-dependent BK currents: consequences of rapid inactivation by a novel beta subunit., Xia XM, Ding JP, Zeng XH, Duan KL, Lingle CJ., J Neurosci. July 1, 2000; 20 (13): 4890-903.

Gating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH(2)- and COOH termini., Zeng XH, Ding JP, Xia XM, Lingle CJ., J Gen Physiol. June 1, 2001; 117 (6): 607-28.                                      

Inactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockade., Lingle CJ, Zeng XH, Ding JP, Xia XM., J Gen Physiol. June 1, 2001; 117 (6): 583-606.                                                

Allosteric regulation of BK channel gating by Ca(2+) and Mg(2+) through a nonselective, low affinity divalent cation site., Zhang X, Solaro CR, Lingle CJ., J Gen Physiol. November 1, 2001; 118 (5): 607-36.                                  

Gating and conductance properties of BK channels are modulated by the S9-S10 tail domain of the alpha subunit. A study of mSlo1 and mSlo3 wild-type and chimeric channels., Moss BL, Magleby KL., J Gen Physiol. December 1, 2001; 118 (6): 711-34.                        

SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction., Wang ZW, Saifee O, Nonet ML, Salkoff L., Neuron. December 6, 2001; 32 (5): 867-81.

Consequences of the stoichiometry of Slo1 alpha and auxiliary beta subunits on functional properties of large-conductance Ca2+-activated K+ channels., Wang YW, Ding JP, Xia XM, Lingle CJ., J Neurosci. March 1, 2002; 22 (5): 1550-61.

Steady-state and closed-state inactivation properties of inactivating BK channels., Ding JP, Lingle CJ., Biophys J. May 1, 2002; 82 (5): 2448-65.

Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity., Bao L, Rapin AM, Holmstrand EC, Cox DH., J Gen Physiol. August 1, 2002; 120 (2): 173-89.                  

Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels., Horrigan FT, Aldrich RW., J Gen Physiol. September 1, 2002; 120 (3): 267-305.                              

Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels., Qian X, Nimigean CM, Niu X, Moss BL, Magleby KL., J Gen Physiol. December 1, 2002; 120 (6): 829-43.              

Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues., Xia XM, Ding JP, Lingle CJ., J Gen Physiol. February 1, 2003; 121 (2): 125-48.                                

The sodium-activated potassium channel is encoded by a member of the Slo gene family., Yuan A, Santi CM, Wei A, Wang ZW, Pollak K, Nonet M, Kaczmarek L, Crowder CM, Salkoff L., Neuron. March 6, 2003; 37 (5): 765-73.

Distinct regions of the slo subunit determine differential BKCa channel responses to ethanol., Liu P, Liu J, Huang W, Li MD, Dopico AM., Alcohol Clin Exp Res. October 1, 2003; 27 (10): 1640-4.

Selective regulation of xSlo splice variants during Xenopus embryogenesis., Kukuljan M, Taylor A, Chouinard H, Olguin P, Rojas CV, Ribera AB., J Neurophysiol. November 1, 2003; 90 (5): 3352-60.  

Functional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channel., Ha TS, Heo MS, Park CS., Biophys J. May 1, 2004; 86 (5): 2871-82.

Ligand-dependent activation of Slo family channels is defined by interchangeable cytosolic domains., Xia XM, Zhang X, Lingle CJ., J Neurosci. June 16, 2004; 24 (24): 5585-91.

Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part II: Neutralization of aspartate 292 reduces long channel openings and gating current slow component., Haug T, Olcese R, Toro L, Stefani E., J Gen Physiol. August 1, 2004; 124 (2): 185-97.                  

Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part I: Aspartate 292 modulates K+ conduction by external surface charge effect., Haug T, Sigg D, Ciani S, Toro L, Stefani E, Olcese R., J Gen Physiol. August 1, 2004; 124 (2): 173-84.              

BmBKTx1, a novel Ca2+-activated K+ channel blocker purified from the Asian scorpion Buthus martensi Karsch., Xu CQ, Brône B, Wicher D, Bozkurt O, Lu WY, Huys I, Han YH, Tytgat J, Van Kerkhove E, Chi CW., J Biol Chem. August 13, 2004; 279 (33): 34562-9.

Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites., Zeng XH, Xia XM, Lingle CJ., J Gen Physiol. March 1, 2005; 125 (3): 273-86.              

Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner., Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC., J Pharmacol Exp Ther. September 1, 2005; 314 (3): 1353-61.

CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels., Liu J, Asuncion-Chin M, Liu P, Dopico AM., Nat Neurosci. January 1, 2006; 9 (1): 41-9.

Direct observation of a preinactivated, open state in BK channels with beta2 subunits., Benzinger GR, Xia XM, Lingle CJ., J Gen Physiol. February 1, 2006; 127 (2): 119-31.                

Opposite regulation of Slick and Slack K+ channels by neuromodulators., Santi CM, Ferreira G, Yang B, Gazula VR, Butler A, Wei A, Kaczmarek LK, Salkoff L., J Neurosci. May 10, 2006; 26 (19): 5059-68.

Slo3 K+ channels: voltage and pH dependence of macroscopic currents., Zhang X, Zeng X, Lingle CJ., J Gen Physiol. September 1, 2006; 128 (3): 317-36.                            

pH-regulated Slo3 K+ channels: properties of unitary currents., Zhang X, Zeng X, Xia XM, Lingle CJ., J Gen Physiol. September 1, 2006; 128 (3): 301-15.                          

Interaction sites between the Slo1 pore and the NH2 terminus of the beta2 subunit, probed with a three-residue sensor., Li H, Yao J, Tong X, Guo Z, Wu Y, Sun L, Pan N, Wu H, Xu T, Ding J., J Biol Chem. June 15, 2007; 282 (24): 17720-8.

Characterization of voltage-and Ca2+-activated K+ channels in rat dorsal root ganglion neurons., Li W, Gao SB, Lv CX, Wu Y, Guo ZH, Ding JP, Xu T., J Cell Physiol. August 1, 2007; 212 (2): 348-57.

Presynaptic Ca2+/calmodulin-dependent protein kinase II modulates neurotransmitter release by activating BK channels at Caenorhabditis elegans neuromuscular junction., Liu Q, Chen B, Ge Q, Wang ZW., J Neurosci. September 26, 2007; 27 (39): 10404-13.

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels., Bentzen BH, Nardi A, Calloe K, Madsen LS, Olesen SP, Grunnet M., Mol Pharmacol. October 1, 2007; 72 (4): 1033-44.

Mg2+ enhances voltage sensor/gate coupling in BK channels., Horrigan FT, Ma Z., J Gen Physiol. January 1, 2008; 131 (1): 13-32.                

The sodium-activated potassium channel Slack is modulated by hypercapnia and acidosis., Ruffin VA, Gu XQ, Zhou D, Douglas RM, Sun X, Trouth CO, Haddad GG., Neuroscience. January 24, 2008; 151 (2): 410-8.

Species-specific Differences among KCNMB3 BK beta3 auxiliary subunits: some beta3 N-terminal variants may be primate-specific subunits., Zeng X, Xia XM, Lingle CJ., J Gen Physiol. July 1, 2008; 132 (1): 115-29.                    

Ethanol modulates BKCa channels by acting as an adjuvant of calcium., Liu J, Vaithianathan T, Manivannan K, Parrill A, Dopico AM., Mol Pharmacol. September 1, 2008; 74 (3): 628-40.

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