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Summary Expression Phenotypes Gene Literature (117) GO Terms (4) Nucleotides (52) Proteins (37) Interactants (118) Wiki
XB-GENEPAGE-991583

Papers associated with kcna2



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Drug-induced ion channel opening tuned by the voltage sensor charge profile., Ottosson NE, Liin SI, Elinder F., J Gen Physiol. February 1, 2014; 143 (2): 173-82.              


A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris., Dhillon MS, Cockcroft CJ, Munsey T, Smith KJ, Powell AJ, Carter P, Wrighton DC, Rong HL, Yusaf SP, Sivaprasadarao A., Sci Rep. February 26, 2014; 4 4201.              


Electrophysiological characterization of Ts6 and Ts7, K⁺ channel toxins isolated through an improved Tityus serrulatus venom purification procedure., Cerni FA, Pucca MB, Peigneur S, Cremonez CM, Bordon KC, Tytgat J, Arantes EC., Toxins (Basel). February 28, 2014; 6 (3): 892-913.              


Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel., Zaydman MA, Kasimova MA, McFarland K, Beller Z, Hou P, Kinser HE, Liang H, Zhang G, Shi J, Tarek M, Cui J., Elife. March 12, 2014; 3 e03606.                        


A self-consistent approach for determining pairwise interactions that underlie channel activation., Chowdhury S, Haehnel BM, Chanda B., J Gen Physiol. November 1, 2014; 144 (5): 441-55.              


Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels., Chowdhury S, Haehnel BM, Chanda B., J Gen Physiol. November 1, 2014; 144 (5): 457-67.            


Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels., Gupta K, Zamanian M, Bae C, Milescu M, Krepkiy D, Tilley DC, Sack JT, Yarov-Yarovoy V, Kim JI, Swartz KJ., Elife. January 6, 2015; 4 e06774.                


Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy., Maity S, Mazzolini M, Arcangeletti M, Valbuena A, Fabris P, Lazzarino M, Torre V., Nat Commun. May 12, 2015; 6 7093.              


Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic Action., Liang Q, Anderson WD, Jones ST, Souza CS, Hosoume JM, Treptow W, Covarrubias M., PLoS One. November 24, 2015; 10 (11): e0143363.                    


Congruent pattern of accessibility identifies minimal pore gate in a non-symmetric voltage-gated sodium channel., Oelstrom K, Chanda B., Nat Commun. May 17, 2016; 7 11608.


A recurrent mutation in KCNA2 as a novel cause of hereditary spastic paraplegia and ataxia., Helbig KL, Hedrich UB, Shinde DN, Krey I, Teichmann AC, Hentschel J, Schubert J, Chamberlin AC, Huether R, Lu HM, Alcaraz WA, Tang S, Jungbluth C, Dugan SL, Vainionpää L, Karle KN, Synofzik M, Schöls L, Schüle R, Lehesjoki AE, Helbig I, Lerche H, Lemke JR., Ann Neurol. October 1, 2016; 80 (4):     


Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1., Elinder F, Madeja M, Zeberg H, Århem P., Biophys J. October 18, 2016; 111 (8): 1679-1691.


Dominant KCNA2 mutation causes episodic ataxia and pharmacoresponsive epilepsy., Corbett MA, Bellows ST, Li M, Carroll R, Micallef S, Carvill GL, Myers CT, Howell KB, Maljevic S, Lerche H, Gazina EV, Mefford HC, Bahlo M, Berkovic SF, Petrou S, Scheffer IE, Gecz J., Neurology. November 8, 2016; 87 (19): 1975-1984.


C-Terminal residues in small potassium channel blockers OdK1 and OSK3 from scorpion venom fine-tune the selectivity., Kuzmenkov AI, Peigneur S, Chugunov AO, Tabakmakher VM, Efremov RG, Tytgat J, Grishin EV, Vassilevski AA., Biochim Biophys Acta Proteins Proteom. May 1, 2017; 1865 (5): 465-472.


Clinical spectrum and genotype-phenotype associations of KCNA2-related encephalopathies., Masnada S, Hedrich UBS, Gardella E, Schubert J, Kaiwar C, Klee EW, Lanpher BC, Gavrilova RH, Synofzik M, Bast T, Gorman K, King MD, Allen NM, Conroy J, Ben Zeev B, Tzadok M, Korff C, Dubois F, Ramsey K, Narayanan V, Serratosa JM, Giraldez BG, Helbig I, Marsh E, O'Brien M, Bergqvist CA, Binelli A, Porter B, Zaeyen E, Horovitz DD, Wolff M, Marjanovic D, Caglayan HS, Arslan M, Pena SDJ, Sisodiya SM, Balestrini S, Syrbe S, Veggiotti P, Lemke JR, Møller RS, Lerche H, Rubboli G., Brain. September 1, 2017; 140 (9): 2337-2354.


Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels., Bu W, Liang Q, Zhi L, Maciunas L, Loll PJ, Eckenhoff RG, Covarrubias M., Mol Neurobiol. February 1, 2018; 55 (2): 1692-1702.


Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., Manville RW, Abbott GW., J Pharmacol Exp Ther. June 1, 2020; 373 (3): 391-401.

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