The gcg gene encodes glucagon, a peptide hormone functioning as a signaling molecule involved in glucose metabolism regulation. In embryos and adults, it is expressed in the pancreas within alpha cells...[+]

The gcg gene encodes glucagon, a peptide hormone functioning as a signaling molecule involved in glucose metabolism regulation. In embryos and adults, it is expressed in the pancreas within alpha cells of the islets of langerhans and in distinct intestinal endocrine cells. The protein localizes to secretory granules. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD