The gene fzd9 encodes a G-protein coupled receptor localized to the plasma membrane which functions as a Wnt ligand receptor involved in canonical beta-catenin signaling and non-canonical planar cell p...[+]

The gene fzd9 encodes a G-protein coupled receptor localized to the plasma membrane which functions as a Wnt ligand receptor involved in canonical beta-catenin signaling and non-canonical planar cell polarity pathways during embryonic development. Its roles include neural crest specification, migration of cranial ganglia precursors, and regulation of convergent extension movements in gastrulating embryos; expression is documented in the neural plate border, migrating neural crest cells, and cranial ganglia anlagen. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD