The noxo1 gene encodes a cytosolic organizer protein that forms part of the NADPH oxidase complex, which produces reactive oxygen species (ROS). This protein localizes to the cytosol and translocates t...[+]

The noxo1 gene encodes a cytosolic organizer protein that forms part of the NADPH oxidase complex, which produces reactive oxygen species (ROS). This protein localizes to the cytosol and translocates to the membrane upon complex assembly. Expression is detected in oocytes, throughout early embryonic development, and in adult tissues including skin and kidney. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD