Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (4) GO Terms (30) Nucleotides (134) Proteins (40) Interactants (571) Wiki
XB-GENEPAGE-482850
???displayGene.symbol???:
 spred1

???displayGene.name???: 
sprouty related, EVH1 domain containing 1

???displayGene.synonyms???
Xspred1 , Xtspred1 ( Nomenclature history )

???displayGene.geneFunction???
regulation of signal transduction

AI Protein Function :
The protein functions as a negative regulator of the Ras/MAPK/ERK signaling pathway. It is a cytoplasmic sprouty-related EVH1 domain-containing protein that localizes to the cytoplasm and inhibits fibr...[+]


InterPro :
KBD, Sprouty, PH-like dom sf, SPRE EVH1, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Legius syndrome

MIM:
LEGIUS SYNDROME; LGSS

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info