The gene polrmt encodes a DNA-directed RNA polymerase which is localized to the mitochondrion and functions in mitochondrial DNA transcription. This single subunit polymerase transcribes the mitochondr...[+]

The gene polrmt encodes a DNA-directed RNA polymerase which is localized to the mitochondrion and functions in mitochondrial DNA transcription. This single subunit polymerase transcribes the mitochondrial genome to produce RNAs necessary for oxidative phosphorylation. Expression has been documented in the ovary, testis, brain, eye, heart, and muscle. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD