The gene ldb3 encodes a cytoskeletal protein with lim domains expressed in the heart and skeletal muscle. The protein localizes to the Z-disc of myofibrils, functioning in sarcomere organization and st...[+]

The gene ldb3 encodes a cytoskeletal protein with lim domains expressed in the heart and skeletal muscle. The protein localizes to the Z-disc of myofibrils, functioning in sarcomere organization and stability during cardiac and skeletal muscle development from embryonic stages through adulthood. [-]

             dilated cardiomyopathy 1C

          CARDIOMYOPATHY, DILATED, 1C, WITH OR WITHOUT LEFT VENTRICULAR NONCOMPACTION; CMD

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD