znf609 encodes a zinc finger protein that functions as a transcription factor in xenopus laevis and xenopus tropicalis, involved in embryonic development, particularly in neural crest formation and neu...[+]

znf609 encodes a zinc finger protein that functions as a transcription factor in xenopus laevis and xenopus tropicalis, involved in embryonic development, particularly in neural crest formation and neural tube development. The protein localizes to the nucleus and acts as a transcriptional regulator, influencing gene expression during embryogenesis. It is expressed in specific tissues including the neural tube, neural crest, and developing brain regions. The protein contains C2H2-type zinc finger domains, which facilitate DNA binding and transcriptional regulation. In xenopus, znf609 is crucial for proper neural development and is involved in regulating genes involved in neural differentiation and patterning. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD